High-intensity focused ultrasound treatment for large and small solitary uterine fibroids

This retrospective study used data from patients treated for uterine fibroids with ultrasound-guided high-intensity focused ultrasound (USgHIFU) from April 2015 to April 2019. One hundred and seven patients with solitary fibroids were divided into two groups: (1) the L group with larger fibroids (≥1...

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Main Authors: Chih-Ting Chang, Cherng-Jye Jeng, Cheng-Yu Long, Linus T. Chuang, Jenta Shen
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:International Journal of Hyperthermia
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Online Access:https://www.tandfonline.com/doi/10.1080/02656736.2022.2039788
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author Chih-Ting Chang
Cherng-Jye Jeng
Cheng-Yu Long
Linus T. Chuang
Jenta Shen
author_facet Chih-Ting Chang
Cherng-Jye Jeng
Cheng-Yu Long
Linus T. Chuang
Jenta Shen
author_sort Chih-Ting Chang
collection DOAJ
description This retrospective study used data from patients treated for uterine fibroids with ultrasound-guided high-intensity focused ultrasound (USgHIFU) from April 2015 to April 2019. One hundred and seven patients with solitary fibroids were divided into two groups: (1) the L group with larger fibroids (≥10 cm) and (2) the S group with smaller fibroids (<10 cm). Using magnetic resonance imaging (MRI), we examined the efficacy of high-intensity focused ultrasound (HIFU) ablation by comparing uterine and fibroid volumes before and three months after the procedure. The three-month follow-up clinical visit used a visual analog scale and a uterine fibroid symptom health-related quality of life questionnaire to evaluate clinical symptoms. Both the L and S groups had significant reduction in uterine and fibroid volumes, but the rate was significantly higher in the S group (p < 0.05). Both groups also had improvements in clinical symptoms, but there was no statistical difference. USgHIFU reduced the size of both large and small fibroids but was most effective on fibroids smaller than 10 cm. Both the L and S groups had improved dysmenorrhea symptoms and quality of life.
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issn 0265-6736
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publishDate 2022-12-01
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series International Journal of Hyperthermia
spelling doaj-art-068f579cd4794551bbea9c9634e4e1702025-08-20T02:40:42ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572022-12-0139148548910.1080/02656736.2022.2039788High-intensity focused ultrasound treatment for large and small solitary uterine fibroidsChih-Ting Chang0Cherng-Jye Jeng1Cheng-Yu Long2Linus T. Chuang3Jenta Shen4Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, TaiwanDepartment of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Show Chwan Hospital, Taipei, TaiwanDepartment of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, TaiwanDepartment of Obstetrics and Gynecology, Western Connecticut Health Network, Larner College of Medicine at The University of Vermont, Danbury, CT, USADepartment of Obstetrics and Gynecology, California Pacific Medical Center, San Francisco, CA, USAThis retrospective study used data from patients treated for uterine fibroids with ultrasound-guided high-intensity focused ultrasound (USgHIFU) from April 2015 to April 2019. One hundred and seven patients with solitary fibroids were divided into two groups: (1) the L group with larger fibroids (≥10 cm) and (2) the S group with smaller fibroids (<10 cm). Using magnetic resonance imaging (MRI), we examined the efficacy of high-intensity focused ultrasound (HIFU) ablation by comparing uterine and fibroid volumes before and three months after the procedure. The three-month follow-up clinical visit used a visual analog scale and a uterine fibroid symptom health-related quality of life questionnaire to evaluate clinical symptoms. Both the L and S groups had significant reduction in uterine and fibroid volumes, but the rate was significantly higher in the S group (p < 0.05). Both groups also had improvements in clinical symptoms, but there was no statistical difference. USgHIFU reduced the size of both large and small fibroids but was most effective on fibroids smaller than 10 cm. Both the L and S groups had improved dysmenorrhea symptoms and quality of life.https://www.tandfonline.com/doi/10.1080/02656736.2022.2039788High-intensity focused ultrasounduterine fibroidleiomyoma
spellingShingle Chih-Ting Chang
Cherng-Jye Jeng
Cheng-Yu Long
Linus T. Chuang
Jenta Shen
High-intensity focused ultrasound treatment for large and small solitary uterine fibroids
International Journal of Hyperthermia
High-intensity focused ultrasound
uterine fibroid
leiomyoma
title High-intensity focused ultrasound treatment for large and small solitary uterine fibroids
title_full High-intensity focused ultrasound treatment for large and small solitary uterine fibroids
title_fullStr High-intensity focused ultrasound treatment for large and small solitary uterine fibroids
title_full_unstemmed High-intensity focused ultrasound treatment for large and small solitary uterine fibroids
title_short High-intensity focused ultrasound treatment for large and small solitary uterine fibroids
title_sort high intensity focused ultrasound treatment for large and small solitary uterine fibroids
topic High-intensity focused ultrasound
uterine fibroid
leiomyoma
url https://www.tandfonline.com/doi/10.1080/02656736.2022.2039788
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AT cherngjyejeng highintensityfocusedultrasoundtreatmentforlargeandsmallsolitaryuterinefibroids
AT chengyulong highintensityfocusedultrasoundtreatmentforlargeandsmallsolitaryuterinefibroids
AT linustchuang highintensityfocusedultrasoundtreatmentforlargeandsmallsolitaryuterinefibroids
AT jentashen highintensityfocusedultrasoundtreatmentforlargeandsmallsolitaryuterinefibroids