An In vivo Metabolic Reaction-Based Mass Difference Screening Strategy for Comprehensive Metabolite Profiling of the Huangqi-Danshen Herb Pair Using Ultra-High-Performance Liquid Chromatography Coupled with Quadrupole-Time-of-Flight Mass Spectrometry
Objective: The absorbed prototypes and metabolites of traditional Chinese medicines in vivo are crucial for identifying their biological functions. However, comprehensive profiling of constituents in vivo is difficult owing to endogenous interference and low metabolite abundance. Therefore, a system...
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| Main Authors: | Chen-Xi Liu, Xin-Lu Li, Cai-Yi Ma, Meng Ding, Ping Li, Hua Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | World Journal of Traditional Chinese Medicine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/wjtcm.wjtcm_4_25 |
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