Research progress on the biosynthesis, metabolic engineering, and pharmacology of bioactive compounds from the Lonicera genus
The Lonicera genus with medicinal and edible characteristics is a rich source of bioactive compounds that together account for numerous health benefits. Plants within this genus have been used traditionally in China to treat heat-related illnesses, viral respiratory infections, skin diseases, and in...
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| Format: | Article |
| Language: | English |
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Maximum Academic Press
2024-01-01
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| Series: | Medicinal Plant Biology |
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| Online Access: | https://www.maxapress.com/article/doi/10.48130/mpb-0024-0008 |
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| author | Xiaojie Chen Weiqiang Li Xu Lu Lam-Son Phan Tran Raphael N. Alolga Xiaojian Yin |
| author_facet | Xiaojie Chen Weiqiang Li Xu Lu Lam-Son Phan Tran Raphael N. Alolga Xiaojian Yin |
| author_sort | Xiaojie Chen |
| collection | DOAJ |
| description | The Lonicera genus with medicinal and edible characteristics is a rich source of bioactive compounds that together account for numerous health benefits. Plants within this genus have been used traditionally in China to treat heat-related illnesses, viral respiratory infections, skin diseases, and inflammation for thousands of years. The main bioactive compounds include chlorogenic acids, flavonoids, iridoids, and triterpene saponins. Aside from the role of this genus as a valuable medicinal resource, constituent members have also been used in the food and cosmetic industries. Due to the huge demand for plants within the Lonicera genus, and the propensity for overexploitation of the wild resources of Lonicera, there is a need to meet this demand via alternative and efficient strategies such as metabolic engineering and green production. Here, we provide a comprehensive review of relevant scientific literature covering the structure, biosynthesis, metabolic engineering, pharmacology and phylogenetic analysis of the main bioactive constituents of the Lonicera genus. Finally, we proffer suggestions on the prospects of fully exploiting and utilizing plants of the Lonicera genus as useful medicinal plant resources. |
| format | Article |
| id | doaj-art-0672fe826d3144dfb7030fb587d922ba |
| institution | DOAJ |
| issn | 2835-6969 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Maximum Academic Press |
| record_format | Article |
| series | Medicinal Plant Biology |
| spelling | doaj-art-0672fe826d3144dfb7030fb587d922ba2025-08-20T03:18:23ZengMaximum Academic PressMedicinal Plant Biology2835-69692024-01-013111210.48130/mpb-0024-0008mpb-0024-0008Research progress on the biosynthesis, metabolic engineering, and pharmacology of bioactive compounds from the Lonicera genusXiaojie Chen0Weiqiang Li1Xu Lu2Lam-Son Phan Tran3Raphael N. Alolga4Xiaojian Yin5State Key Laboratory of Natural Medicines, Department of Pharmacognosy, Institute of Pharmaceutical Science, China Pharmaceutical University, Nanjing 210009, ChinaState Key Laboratory of Black Soils Conservation and Utilization, Key Laboratory of Soybean Molecular Design Breeding, Northeast Institute of Geography and Agroecology Chinese Academy of Sciences, Changchun, 130102, ChinaState Key Laboratory of Natural Medicines, Department of Pharmacognosy, Institute of Pharmaceutical Science, China Pharmaceutical University, Nanjing 210009, ChinaInstitute of Genomics for Crop Abiotic Stress Tolerance, Department of Plant and Soil Science, Texas Tech University, Lubbock, TX 79409, USAState Key Laboratory of Natural Medicines, Department of Pharmacognosy, Institute of Pharmaceutical Science, China Pharmaceutical University, Nanjing 210009, ChinaState Key Laboratory of Natural Medicines, Department of Pharmacognosy, Institute of Pharmaceutical Science, China Pharmaceutical University, Nanjing 210009, ChinaThe Lonicera genus with medicinal and edible characteristics is a rich source of bioactive compounds that together account for numerous health benefits. Plants within this genus have been used traditionally in China to treat heat-related illnesses, viral respiratory infections, skin diseases, and inflammation for thousands of years. The main bioactive compounds include chlorogenic acids, flavonoids, iridoids, and triterpene saponins. Aside from the role of this genus as a valuable medicinal resource, constituent members have also been used in the food and cosmetic industries. Due to the huge demand for plants within the Lonicera genus, and the propensity for overexploitation of the wild resources of Lonicera, there is a need to meet this demand via alternative and efficient strategies such as metabolic engineering and green production. Here, we provide a comprehensive review of relevant scientific literature covering the structure, biosynthesis, metabolic engineering, pharmacology and phylogenetic analysis of the main bioactive constituents of the Lonicera genus. Finally, we proffer suggestions on the prospects of fully exploiting and utilizing plants of the Lonicera genus as useful medicinal plant resources.https://www.maxapress.com/article/doi/10.48130/mpb-0024-0008lonicerabiosynthesismetabolic engineeringpharmacology |
| spellingShingle | Xiaojie Chen Weiqiang Li Xu Lu Lam-Son Phan Tran Raphael N. Alolga Xiaojian Yin Research progress on the biosynthesis, metabolic engineering, and pharmacology of bioactive compounds from the Lonicera genus Medicinal Plant Biology lonicera biosynthesis metabolic engineering pharmacology |
| title | Research progress on the biosynthesis, metabolic engineering, and pharmacology of bioactive compounds from the Lonicera genus |
| title_full | Research progress on the biosynthesis, metabolic engineering, and pharmacology of bioactive compounds from the Lonicera genus |
| title_fullStr | Research progress on the biosynthesis, metabolic engineering, and pharmacology of bioactive compounds from the Lonicera genus |
| title_full_unstemmed | Research progress on the biosynthesis, metabolic engineering, and pharmacology of bioactive compounds from the Lonicera genus |
| title_short | Research progress on the biosynthesis, metabolic engineering, and pharmacology of bioactive compounds from the Lonicera genus |
| title_sort | research progress on the biosynthesis metabolic engineering and pharmacology of bioactive compounds from the lonicera genus |
| topic | lonicera biosynthesis metabolic engineering pharmacology |
| url | https://www.maxapress.com/article/doi/10.48130/mpb-0024-0008 |
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