Wnt signaling as a translational target in rheumatoid and psoriatic arthritis

Wnt signaling as a translational target in rheumatoid and psoriatic arthritis

Abstract Background Rheumatoid arthritis (RA) and Psoriatic arthritis (PsA) are chronic inflammatory diseases mainly affecting joints. RA primarily targets the synovial joints and is characterized by cartilage and bone erosion, whereas PsA is associated with skin and nail psoriasis and is characteri...

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Main Authors: Gloria Riitano, Francesca Spinelli, Valeria Manganelli, Daniela Caissutti, Antonella Capozzi, Cristina Garufi, Tina Garofalo, Roberta Misasi, Maurizio Sorice, Fabrizio Conti, Agostina Longo, Cristiano Alessandri
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Translational Medicine
Subjects:
Rheumatoid arthritis
Psoriatic arthritis
Wnt signaling
DKK1
β-catenin
Online Access:https://doi.org/10.1186/s12967-025-06174-2
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