Histoplasmosis and blastomycosis: Progress and possibilities
Background: Histoplasmosis and blastomycosis are important global fungal infections that primarily start as pulmonary pathogens but can lead to disseminated, fatal disease requiring prolonged antifungal therapy. Objectives: In this narrative review, we aimed to create an approachable resource for cl...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | CMI Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950590925000095 |
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| Summary: | Background: Histoplasmosis and blastomycosis are important global fungal infections that primarily start as pulmonary pathogens but can lead to disseminated, fatal disease requiring prolonged antifungal therapy. Objectives: In this narrative review, we aimed to create an approachable resource for clinicians to guide them and their patients towards timely diagnosis and treatment. Sources: A comprehensive search of the PubMed database from the year 2000 through October 2024 was done to identify papers informing this review. Article references were reviewed for further relevant work. Content: We highlight the similarities, differences, and areas of future work for these dimorphic fungi focusing on the pathogenesis, epidemiology, clinical presentation, diagnostic testing, and treatment. Implications: Histoplasmosis and blastomycosis overlap in many areas, but understanding the differences between these two infections allows clinicians to optimize the management of their patients. |
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| ISSN: | 2950-5909 |