Lobular panniculitis in rheumatic diseases: the authors’ own data

Objective: to study the clinical and laboratory features of lobular panniculitides (LPn) on a cohort of patients referred to the rheumatology center.Patients and methods. The investigation enrolled 687 patients (613 women and 74 men; mean age, 39.7±11.3 and 41.2±12.5 years, respectively) with pannic...

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Main Authors: O. N. Egorova, B. S. Belov, S. G. Radenska-Lopovok
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-03-01
Series:Современная ревматология
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Online Access:https://mrj.ima-press.net/mrj/article/view/993
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author O. N. Egorova
B. S. Belov
S. G. Radenska-Lopovok
author_facet O. N. Egorova
B. S. Belov
S. G. Radenska-Lopovok
author_sort O. N. Egorova
collection DOAJ
description Objective: to study the clinical and laboratory features of lobular panniculitides (LPn) on a cohort of patients referred to the rheumatology center.Patients and methods. The investigation enrolled 687 patients (613 women and 74 men; mean age, 39.7±11.3 and 41.2±12.5 years, respectively) with panniculitis (Pn) who had received outpatient and/or inpatient treatment for diagnosed erythema nodosum or panniculitis at the V.A. Nasonova Research Institute of Rheumatology in 2007–2017.Results and discussion. By applying the diagnostic algorithm developed by the authors and the existing classification of Pn, the investigators diagnosed septal Pn in 430 (62.6%) patients and LPn in 249 (36.2%). The latter was associated with rheumatic diseases (RDs) in 97 (39%) patients. Most (70%) cases were patients with idiopathic LPn (ILPn), which, according to the 10th edition of the International Classification of Diseases, belongs to a group of systemic connective tissue disorders (M35.6), as well as those with systemic lupus erythematosus (SLE) (11.45%), dermatomyositis (DM) (9.37%), and rheumatoid arthritis (7%). This group showed a preponderance of females (the ratio of males to females was 1:7) with the chronic course of the disease mainly in ILPn. The clinical picture corresponded to four types of LPn, which may be of diagnostic and prognostic value in RDs.Conclusion. This investigation confirmed the relevance of studying LPn in RDs because of its negative impact on the course, severity and therapeutic efficiency of the underlying disease.
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spelling doaj-art-066056803c9e49b08d23257ea2db99462025-08-20T03:01:22ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2020-03-01141576110.14412/1996-7012-2020-1-57-612236Lobular panniculitis in rheumatic diseases: the authors’ own dataO. N. Egorova0B. S. Belov1S. G. Radenska-Lopovok2V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)Objective: to study the clinical and laboratory features of lobular panniculitides (LPn) on a cohort of patients referred to the rheumatology center.Patients and methods. The investigation enrolled 687 patients (613 women and 74 men; mean age, 39.7±11.3 and 41.2±12.5 years, respectively) with panniculitis (Pn) who had received outpatient and/or inpatient treatment for diagnosed erythema nodosum or panniculitis at the V.A. Nasonova Research Institute of Rheumatology in 2007–2017.Results and discussion. By applying the diagnostic algorithm developed by the authors and the existing classification of Pn, the investigators diagnosed septal Pn in 430 (62.6%) patients and LPn in 249 (36.2%). The latter was associated with rheumatic diseases (RDs) in 97 (39%) patients. Most (70%) cases were patients with idiopathic LPn (ILPn), which, according to the 10th edition of the International Classification of Diseases, belongs to a group of systemic connective tissue disorders (M35.6), as well as those with systemic lupus erythematosus (SLE) (11.45%), dermatomyositis (DM) (9.37%), and rheumatoid arthritis (7%). This group showed a preponderance of females (the ratio of males to females was 1:7) with the chronic course of the disease mainly in ILPn. The clinical picture corresponded to four types of LPn, which may be of diagnostic and prognostic value in RDs.Conclusion. This investigation confirmed the relevance of studying LPn in RDs because of its negative impact on the course, severity and therapeutic efficiency of the underlying disease.https://mrj.ima-press.net/mrj/article/view/993lobular panniculitisrheumatic diseasesdiagnosisclinical picture
spellingShingle O. N. Egorova
B. S. Belov
S. G. Radenska-Lopovok
Lobular panniculitis in rheumatic diseases: the authors’ own data
Современная ревматология
lobular panniculitis
rheumatic diseases
diagnosis
clinical picture
title Lobular panniculitis in rheumatic diseases: the authors’ own data
title_full Lobular panniculitis in rheumatic diseases: the authors’ own data
title_fullStr Lobular panniculitis in rheumatic diseases: the authors’ own data
title_full_unstemmed Lobular panniculitis in rheumatic diseases: the authors’ own data
title_short Lobular panniculitis in rheumatic diseases: the authors’ own data
title_sort lobular panniculitis in rheumatic diseases the authors own data
topic lobular panniculitis
rheumatic diseases
diagnosis
clinical picture
url https://mrj.ima-press.net/mrj/article/view/993
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AT bsbelov lobularpanniculitisinrheumaticdiseasestheauthorsowndata
AT sgradenskalopovok lobularpanniculitisinrheumaticdiseasestheauthorsowndata