Dual-modal overcoming of physical barriers for improved photodynamic cancer therapy via soft organosilica nanocapsules

Dual-modal overcoming of physical barriers for improved photodynamic cancer therapy via soft organosilica nanocapsules

Abstract Amidst the burgeoning field of cancer nanomedicine, dense extracellular matrices and anomalous vascular structures in the tumor microenvironment (TME) present substantial physical barriers to effective therapeutic delivery. These physical barriers hinder the optimal bioavailability of nanom...

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Bibliographic Details
Main Authors: Wei Lu, Yang Li, Xiaojun Zhang, Ning Wang, Dong Chen, Yatong Zhao, Guang Li, Xuzhi Shi, Xiaobo Ma, Xiaodan Su, Feng Wang, Chuqiang Shu, Kun Chen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Nanobiotechnology
Subjects:
Mesoporous organosilica
Soft nanoplatform
Tumor penetration
Photodynamic treatment
Online Access:https://doi.org/10.1186/s12951-024-02945-z
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