THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS
The paper analyzes two matching-adjusted indirect comparison-based investigations of the efficacy of adalimumab (ADA) and secukinumab (SCM) in active ankylosing spondylitis, which have been recently reported at the EULAR Congress (London, 2016). One study sponsored by AbbVie was conducted to determi...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2016-12-01
|
| Series: | Современная ревматология |
| Subjects: | |
| Online Access: | https://mrj.ima-press.net/mrj/article/view/721 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849691586978381824 |
|---|---|
| author | Sh. F. Erdes |
| author_facet | Sh. F. Erdes |
| author_sort | Sh. F. Erdes |
| collection | DOAJ |
| description | The paper analyzes two matching-adjusted indirect comparison-based investigations of the efficacy of adalimumab (ADA) and secukinumab (SCM) in active ankylosing spondylitis, which have been recently reported at the EULAR Congress (London, 2016). One study sponsored by AbbVie was conducted to determine the short-term (16-week) comparative clinical and economic efficacy of the test drugs and the other was supported by Novartis to reveal long-term (52-week), only clinical efficacy. Both studies have shown that the short-term efficacy ofADAand SCM is practically similar; however, the latter has a better long-term clinical efficacy. A pharmacoeconomic analysis of both drugs used during the first 12 weeks has demonstrated some advantage ofADA. |
| format | Article |
| id | doaj-art-063eb3296f74465cbcfcb53ce5cd9985 |
| institution | DOAJ |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2016-12-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-063eb3296f74465cbcfcb53ce5cd99852025-08-20T03:20:59ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2016-12-01104646810.14412/1996-7012-2016-4-64-682006THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITISSh. F. Erdes0V.A. Nasonova Research Institute of RheumatologyThe paper analyzes two matching-adjusted indirect comparison-based investigations of the efficacy of adalimumab (ADA) and secukinumab (SCM) in active ankylosing spondylitis, which have been recently reported at the EULAR Congress (London, 2016). One study sponsored by AbbVie was conducted to determine the short-term (16-week) comparative clinical and economic efficacy of the test drugs and the other was supported by Novartis to reveal long-term (52-week), only clinical efficacy. Both studies have shown that the short-term efficacy ofADAand SCM is practically similar; however, the latter has a better long-term clinical efficacy. A pharmacoeconomic analysis of both drugs used during the first 12 weeks has demonstrated some advantage ofADA.https://mrj.ima-press.net/mrj/article/view/721ankylosing spondylitismatching-adjusted indirect comparison methodadalimumabsecukinumab |
| spellingShingle | Sh. F. Erdes THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS Современная ревматология ankylosing spondylitis matching-adjusted indirect comparison method adalimumab secukinumab |
| title | THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS |
| title_full | THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS |
| title_fullStr | THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS |
| title_full_unstemmed | THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS |
| title_short | THE POSSIBILITIES AND RESULTS OF INDIRECT COMPARISON OF BIOLOGICAL AGENTS IN ANKYLOSING SPONDYLITIS |
| title_sort | possibilities and results of indirect comparison of biological agents in ankylosing spondylitis |
| topic | ankylosing spondylitis matching-adjusted indirect comparison method adalimumab secukinumab |
| url | https://mrj.ima-press.net/mrj/article/view/721 |
| work_keys_str_mv | AT shferdes thepossibilitiesandresultsofindirectcomparisonofbiologicalagentsinankylosingspondylitis AT shferdes possibilitiesandresultsofindirectcomparisonofbiologicalagentsinankylosingspondylitis |