Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome

Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome

Abstract Preeclampsia is a leading cause of morbidity and mortality in pregnant women, affecting 5–8% of gestations worldwide. Its development is influenced by maternal immune abnormalities, metabolic disorders, and gut dysbiosis. In this study, we show that gut dysbiosis in pregnant C57BL/6J dams l...

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Main Authors: Silvia Giugliano, Andrea Gatti, Martina Rusin, Tilo Schorn, Silvia Pimazzoni, Michela Calanni-Pileri, Valentina Fraccascia, Sara Carloni, Maria Rescigno
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58533-8
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