An Unusual Case of Mullerian Choristomas in the Lumbar Region Presented as Spinal Dysraphism
A choristoma is a benign growth of microscopically normal tissue that resembles a tumor and develops in an unusual place. Mullerian choristomas in connection with spinal dysraphism are incredibly uncommon; less than 10 cases have been reported in English literature. Here, we present a case of a 39-y...
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| Language: | English |
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Wolters Kluwer Medknow Publications
2025-05-01
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| Series: | Indian Spine Journal |
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| Online Access: | https://doi.org/10.4103/isj.isj_67_24 |
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| author | Yaminy Pradeep Ingale Arpana Dharwadkar Sushama Gurwale Charusheela Gore |
| author_facet | Yaminy Pradeep Ingale Arpana Dharwadkar Sushama Gurwale Charusheela Gore |
| author_sort | Yaminy Pradeep Ingale |
| collection | DOAJ |
| description | A choristoma is a benign growth of microscopically normal tissue that resembles a tumor and develops in an unusual place. Mullerian choristomas in connection with spinal dysraphism are incredibly uncommon; less than 10 cases have been reported in English literature. Here, we present a case of a 39-year-old female who has had lower back swelling since birth, along with difficulty in walking and lower-limb pain for 8 months. A computed tomography scan and magnetic resonance imaging of the spine show spinal dysraphism–spina bifida at L3–L4 level with lipomeningocele. An excisional biopsy of the swelling was done and sent for histopathology. A biopsy shows the presence of ectopic endometrial and fallopian tissue along with fibro-fatty tissue, which is confirmed by immunohistochemistry. Smooth muscles, stromal cells, and epithelium had positive estrogen receptors, according to immunohistochemistry. In addition, the stromal cells demonstrated a cluster of differentiation 10 positivity, indicating Mullerian derivation and the epithelial cells were also positive for cytokeratin 7. From the results of immunohistochemistry and histopathology, we gave the diagnosis of Mullerian choristoma with lipomyelocele. |
| format | Article |
| id | doaj-art-061fd36fbc524a32b325ea2324b4004e |
| institution | OA Journals |
| issn | 2589-5079 2589-5087 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
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| series | Indian Spine Journal |
| spelling | doaj-art-061fd36fbc524a32b325ea2324b4004e2025-08-20T02:36:42ZengWolters Kluwer Medknow PublicationsIndian Spine Journal2589-50792589-50872025-05-018216717110.4103/isj.isj_67_24An Unusual Case of Mullerian Choristomas in the Lumbar Region Presented as Spinal DysraphismYaminy Pradeep IngaleArpana DharwadkarSushama GurwaleCharusheela GoreA choristoma is a benign growth of microscopically normal tissue that resembles a tumor and develops in an unusual place. Mullerian choristomas in connection with spinal dysraphism are incredibly uncommon; less than 10 cases have been reported in English literature. Here, we present a case of a 39-year-old female who has had lower back swelling since birth, along with difficulty in walking and lower-limb pain for 8 months. A computed tomography scan and magnetic resonance imaging of the spine show spinal dysraphism–spina bifida at L3–L4 level with lipomeningocele. An excisional biopsy of the swelling was done and sent for histopathology. A biopsy shows the presence of ectopic endometrial and fallopian tissue along with fibro-fatty tissue, which is confirmed by immunohistochemistry. Smooth muscles, stromal cells, and epithelium had positive estrogen receptors, according to immunohistochemistry. In addition, the stromal cells demonstrated a cluster of differentiation 10 positivity, indicating Mullerian derivation and the epithelial cells were also positive for cytokeratin 7. From the results of immunohistochemistry and histopathology, we gave the diagnosis of Mullerian choristoma with lipomyelocele.https://doi.org/10.4103/isj.isj_67_24cytokeratin 7estrogen receptorsimmunohistochemistrymullerian choristomas |
| spellingShingle | Yaminy Pradeep Ingale Arpana Dharwadkar Sushama Gurwale Charusheela Gore An Unusual Case of Mullerian Choristomas in the Lumbar Region Presented as Spinal Dysraphism Indian Spine Journal cytokeratin 7 estrogen receptors immunohistochemistry mullerian choristomas |
| title | An Unusual Case of Mullerian Choristomas in the Lumbar Region Presented as Spinal Dysraphism |
| title_full | An Unusual Case of Mullerian Choristomas in the Lumbar Region Presented as Spinal Dysraphism |
| title_fullStr | An Unusual Case of Mullerian Choristomas in the Lumbar Region Presented as Spinal Dysraphism |
| title_full_unstemmed | An Unusual Case of Mullerian Choristomas in the Lumbar Region Presented as Spinal Dysraphism |
| title_short | An Unusual Case of Mullerian Choristomas in the Lumbar Region Presented as Spinal Dysraphism |
| title_sort | unusual case of mullerian choristomas in the lumbar region presented as spinal dysraphism |
| topic | cytokeratin 7 estrogen receptors immunohistochemistry mullerian choristomas |
| url | https://doi.org/10.4103/isj.isj_67_24 |
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