Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle

An important factor affecting the performance of cattle is the satisfaction of animal needs in nutrients, macro- and microelements. High-yielding dairy cows with intense metabolism are especially sensitive to errors in feeding practices, because even minor nutritional or mineral deficiencies cause m...

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Main Author: A. D. Alekseev
Format: Article
Language:English
Published: Da Vinci Media 2022-12-01
Series:Ветеринария сегодня
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Online Access:https://veterinary.arriah.ru/jour/article/view/677
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author A. D. Alekseev
author_facet A. D. Alekseev
author_sort A. D. Alekseev
collection DOAJ
description An important factor affecting the performance of cattle is the satisfaction of animal needs in nutrients, macro- and microelements. High-yielding dairy cows with intense metabolism are especially sensitive to errors in feeding practices, because even minor nutritional or mineral deficiencies cause metabolic disorders leading to immunodeficiency conditions, reduced resistance to infectious agents and raised sensitivity to infections with pathogenic and opportunistic microorganisms. Besides some infections, for example acute respiratory diseases, also result in metabolic disorders, immunosuppression, decrease in the overall resistance of the organism and ultimately in mixed infections. All this is the reason for low efficacy of vaccination against major infectious diseases. The paper presents the results of testing of plant tissue product «Vidoral», developed by the FSBEI HE Ural SAU for prevention of immunodeficiency conditions in cattle, caused by different factors. The product was injected subcutaneously at a dose of 0.025 ml/kg of live weight to cows in late gestation and calves showing mild anemia, low red blood cells counts, leukocytosis, high lymphocyte and monocyte counts and elevated erythrocyte sedimentation rate, which suggest inflammatory processes in the animal body. Fourteen days post injection blood was collected for hematological and biochemical testing. It was demonstrated that the product restores the animal metabolism, improves hematopoiesis and reduces inflammation. It was established that injection of «Vidoral» in combination with vaccination against infectious rhinotracheitis, viral diarrhea, infection with respiratory syncytial virus and parainfluenza-3 virus induced generation of specific antibodies against the abovementioned infections.
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issn 2304-196X
2658-6959
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publishDate 2022-12-01
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series Ветеринария сегодня
spelling doaj-art-06192b21255e49438dfb091614da5dec2025-02-06T09:52:09ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592022-12-0111432633410.29326/2304-196X-2022-11-4-326-334588Metabolic disorders as a factor in pathogenesis of infectious diseases in cattleA. D. Alekseev0Main Directorate of the Federal Penitentiary Service of Russia for the Sverdlovsk Oblast; FSBEI HE «Urals State Agrarian University» (FSBEI HE Ural SAU)An important factor affecting the performance of cattle is the satisfaction of animal needs in nutrients, macro- and microelements. High-yielding dairy cows with intense metabolism are especially sensitive to errors in feeding practices, because even minor nutritional or mineral deficiencies cause metabolic disorders leading to immunodeficiency conditions, reduced resistance to infectious agents and raised sensitivity to infections with pathogenic and opportunistic microorganisms. Besides some infections, for example acute respiratory diseases, also result in metabolic disorders, immunosuppression, decrease in the overall resistance of the organism and ultimately in mixed infections. All this is the reason for low efficacy of vaccination against major infectious diseases. The paper presents the results of testing of plant tissue product «Vidoral», developed by the FSBEI HE Ural SAU for prevention of immunodeficiency conditions in cattle, caused by different factors. The product was injected subcutaneously at a dose of 0.025 ml/kg of live weight to cows in late gestation and calves showing mild anemia, low red blood cells counts, leukocytosis, high lymphocyte and monocyte counts and elevated erythrocyte sedimentation rate, which suggest inflammatory processes in the animal body. Fourteen days post injection blood was collected for hematological and biochemical testing. It was demonstrated that the product restores the animal metabolism, improves hematopoiesis and reduces inflammation. It was established that injection of «Vidoral» in combination with vaccination against infectious rhinotracheitis, viral diarrhea, infection with respiratory syncytial virus and parainfluenza-3 virus induced generation of specific antibodies against the abovementioned infections.https://veterinary.arriah.ru/jour/article/view/677metabolic disorderscattlemetabolic immunodeficiencysecondary immunodeficiencyacute bovine respiratory diseasesfoot infections in cattlefoot rotstaphylococcal infectionstreptococcal infectionspasteurellosisinfectious rhinotracheitisviral diarrheaparainfluenza-3infection with respiratory syncytial virus
spellingShingle A. D. Alekseev
Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle
Ветеринария сегодня
metabolic disorders
cattle
metabolic immunodeficiency
secondary immunodeficiency
acute bovine respiratory diseases
foot infections in cattle
foot rot
staphylococcal infection
streptococcal infections
pasteurellosis
infectious rhinotracheitis
viral diarrhea
parainfluenza-3
infection with respiratory syncytial virus
title Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle
title_full Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle
title_fullStr Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle
title_full_unstemmed Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle
title_short Metabolic disorders as a factor in pathogenesis of infectious diseases in cattle
title_sort metabolic disorders as a factor in pathogenesis of infectious diseases in cattle
topic metabolic disorders
cattle
metabolic immunodeficiency
secondary immunodeficiency
acute bovine respiratory diseases
foot infections in cattle
foot rot
staphylococcal infection
streptococcal infections
pasteurellosis
infectious rhinotracheitis
viral diarrhea
parainfluenza-3
infection with respiratory syncytial virus
url https://veterinary.arriah.ru/jour/article/view/677
work_keys_str_mv AT adalekseev metabolicdisordersasafactorinpathogenesisofinfectiousdiseasesincattle