Burden of Aeromonas hydrophila –associated diarrhea among children younger than 2 years in rural Egyptian community

Introduction: Between 2004 and 2007, a birth cohort of Egyptian children was analysed to evaluate the epidemiology of enteric diseases. Methodology: A stool sample was collected from the study children every two weeks as well as whenever they experienced diarrhea. Samples were tested for routine...

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Main Authors: Adel M Mansour, Rania Abd Elkhalek, Hind I Shaheen, Hanan El Mohammady, Samir Refaey, Khaled Hassan, Mark Riddle, John W Sanders, Peter J Sebeny, Sylvia Y.N. Young, Robert Frenck
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2012-12-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/2390
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author Adel M Mansour
Rania Abd Elkhalek
Hind I Shaheen
Hanan El Mohammady
Samir Refaey
Khaled Hassan
Mark Riddle
John W Sanders
Peter J Sebeny
Sylvia Y.N. Young
Robert Frenck
author_facet Adel M Mansour
Rania Abd Elkhalek
Hind I Shaheen
Hanan El Mohammady
Samir Refaey
Khaled Hassan
Mark Riddle
John W Sanders
Peter J Sebeny
Sylvia Y.N. Young
Robert Frenck
author_sort Adel M Mansour
collection DOAJ
description Introduction: Between 2004 and 2007, a birth cohort of Egyptian children was analysed to evaluate the epidemiology of enteric diseases. Methodology: A stool sample was collected from the study children every two weeks as well as whenever they experienced diarrhea. Samples were tested for routine bacterial pathogens as well as enteropathogenic viruses and parasites. A secondary goal of the study was to evaluate the burden of less commonly reported pathogens including Aeromonas hydrophila. Results: Of the 348 study subjects, 79 had A. hydrophila isolated from their stool at some point during the study.  Thirty-six children had exclusively symptomatic (S) infections while 33 had exclusively asymptomatic (AS) infections. However, 10 children had both S and AS infections. Among symptomatic cases, A. hydrophila was the sole pathogen isolated 36% of the time. An important aspect of A. hydrophila associated diarrhea was the high level of resistance to cephalosporins. Conclusion: Although relatively uncommon, A. hydrophila was found to be associated with diarrhea among children living in Egypt and was frequently multi-drug resistant.
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publisher The Journal of Infection in Developing Countries
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spelling doaj-art-06173ad5ebdf41748127f3ac4f1cbb122025-08-20T02:57:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802012-12-0161210.3855/jidc.2390Burden of Aeromonas hydrophila –associated diarrhea among children younger than 2 years in rural Egyptian communityAdel M Mansour0Rania Abd Elkhalek1Hind I Shaheen2Hanan El Mohammady3Samir Refaey4Khaled Hassan5Mark Riddle6John W Sanders7Peter J Sebeny8Sylvia Y.N. Young9Robert Frenck10US Naval Medical Research Unit No. 3, Cairo, EgyptUS Naval Medical Research Unit No. 3, Cairo, EgyptUS Naval Medical Research Unit No. 3, Cairo, EgyptUS Naval Medical Research Unit No. 3, Cairo, EgyptMinistry of Health, Cairo, EgyptUS Naval Medical Research Unit No. 3, Cairo, EgyptNational Naval Medical Center, Silver Spring, Maryland, USAUS Naval Medical Research Center Detachment, Lima, PeruNational Naval Medical Center, Silver Spring, Maryland, USANavy Environmental and Preventive Medicine Unit 6 Pearl Harbor, HI, USACincinnati Children’s Hospital Medical Center, Ohio, Cincinnati, USA Introduction: Between 2004 and 2007, a birth cohort of Egyptian children was analysed to evaluate the epidemiology of enteric diseases. Methodology: A stool sample was collected from the study children every two weeks as well as whenever they experienced diarrhea. Samples were tested for routine bacterial pathogens as well as enteropathogenic viruses and parasites. A secondary goal of the study was to evaluate the burden of less commonly reported pathogens including Aeromonas hydrophila. Results: Of the 348 study subjects, 79 had A. hydrophila isolated from their stool at some point during the study.  Thirty-six children had exclusively symptomatic (S) infections while 33 had exclusively asymptomatic (AS) infections. However, 10 children had both S and AS infections. Among symptomatic cases, A. hydrophila was the sole pathogen isolated 36% of the time. An important aspect of A. hydrophila associated diarrhea was the high level of resistance to cephalosporins. Conclusion: Although relatively uncommon, A. hydrophila was found to be associated with diarrhea among children living in Egypt and was frequently multi-drug resistant. https://jidc.org/index.php/journal/article/view/2390Aeromonas hydrophiladiarrheachildren
spellingShingle Adel M Mansour
Rania Abd Elkhalek
Hind I Shaheen
Hanan El Mohammady
Samir Refaey
Khaled Hassan
Mark Riddle
John W Sanders
Peter J Sebeny
Sylvia Y.N. Young
Robert Frenck
Burden of Aeromonas hydrophila –associated diarrhea among children younger than 2 years in rural Egyptian community
Journal of Infection in Developing Countries
Aeromonas hydrophila
diarrhea
children
title Burden of Aeromonas hydrophila –associated diarrhea among children younger than 2 years in rural Egyptian community
title_full Burden of Aeromonas hydrophila –associated diarrhea among children younger than 2 years in rural Egyptian community
title_fullStr Burden of Aeromonas hydrophila –associated diarrhea among children younger than 2 years in rural Egyptian community
title_full_unstemmed Burden of Aeromonas hydrophila –associated diarrhea among children younger than 2 years in rural Egyptian community
title_short Burden of Aeromonas hydrophila –associated diarrhea among children younger than 2 years in rural Egyptian community
title_sort burden of aeromonas hydrophila associated diarrhea among children younger than 2 years in rural egyptian community
topic Aeromonas hydrophila
diarrhea
children
url https://jidc.org/index.php/journal/article/view/2390
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