PBertKla: a protein large language model for predicting human lysine lactylation sites

PBertKla: a protein large language model for predicting human lysine lactylation sites

Abstract Background Lactylation is a newly discovered type of post-translational modification, primarily occurring on lysine (K) residues of both histones and non-histones to exert diverse effects on target proteins. Research has shown that lysine lactylation (Kla) modification is ubiquitous in diff...

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Bibliographic Details
Main Authors: Hongyan Lai, Diyu Luo, Mi Yang, Tao Zhu, Huan Yang, Xinwei Luo, Yijie Wei, Sijia Xie, Feitong Hong, Kunxian Shu, Fuying Dao, Hui Ding
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Biology
Subjects:
Protein large language model
BERT
Transformer
Lysine lactylation site
Human
Online Access:https://doi.org/10.1186/s12915-025-02202-1
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