Tick-borne encephalitis in Serbia: A case series
Introduction: In the Europe, the number of tick-borne encephalitis (TBE) has been increased in the last decade, and the number of endemic areas has been also increased and is still growing. In the present case series, we present clinical and socio-epidemiological data of patients with TBE hospitali...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2019-06-01
|
| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/11516 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850148926163779584 |
|---|---|
| author | Jasmina Poluga Aleksandra Barac Natasa Katanic Salvatore Rubino Branko Milosevic Aleksandar Urosevic Nikola Mitrovic Ivana Kelic Jelena Micic Goran Stevanovic |
| author_facet | Jasmina Poluga Aleksandra Barac Natasa Katanic Salvatore Rubino Branko Milosevic Aleksandar Urosevic Nikola Mitrovic Ivana Kelic Jelena Micic Goran Stevanovic |
| author_sort | Jasmina Poluga |
| collection | DOAJ |
| description |
Introduction: In the Europe, the number of tick-borne encephalitis (TBE) has been increased in the last decade, and the number of endemic areas has been also increased and is still growing. In the present case series, we present clinical and socio-epidemiological data of patients with TBE hospitalized in the period of TBE virus epidemic in Serbia.
Methodology: A case series was conducted in Serbia in 2017. Patients with confirmed TBE were included in the study. Biochemical and serological analysis of blood and CSF, as well as radiological imaging (CT and MRI) were done.
Results: In total, 10 patients with TBE were included in the study. M:F ratio was 1.5:1, while average age was 45.1 years. Half of the patients had severe clinical picture. Endocranial CT scan and MRI did not reveal any abnormality, except in the patient with the most severe CNS infection (meningoencephalomyelitis). Mean value of sedimentation and CRP was slightly elevated (29.6 mm/1hours and 20.1 mg/L, respectively) in 80% of the patients, although elevation was almost negligible. The average number of leucocytes in the cerebrospinal fluid (CSF) was 171×106/L, the mean value of the CSF protein was 1.1g/L. There were no fatal outcomes.
Conclusion: Since other CNS infections have similar clinical picture and CSF finding as TBE, serological analysis for TBE should be included in routine diagnostic practice.
|
| format | Article |
| id | doaj-art-0607dfde198f4f20bbeb39686ced71c7 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2019-06-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-0607dfde198f4f20bbeb39686ced71c72025-08-20T02:27:06ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802019-06-01130610.3855/jidc.11516Tick-borne encephalitis in Serbia: A case seriesJasmina Poluga0Aleksandra Barac1Natasa Katanic2Salvatore Rubino3Branko Milosevic4Aleksandar Urosevic5Nikola Mitrovic6Ivana Kelic7Jelena Micic8Goran Stevanovic9Clinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, SerbiaClinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, SerbiaClinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, SerbiaDepartment of Biomedical Sciences, University of Sassari, Sassari, ItalyClinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, SerbiaClinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, SerbiaClinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, SerbiaInstitute for Public Health “Dr Milan Jovanovic Batut”, Belgrade, SerbiaClinic for Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, SerbiaClinic for Infectious and Tropical Diseases, Clinical Centre of Serbia, Belgrade, Serbia Introduction: In the Europe, the number of tick-borne encephalitis (TBE) has been increased in the last decade, and the number of endemic areas has been also increased and is still growing. In the present case series, we present clinical and socio-epidemiological data of patients with TBE hospitalized in the period of TBE virus epidemic in Serbia. Methodology: A case series was conducted in Serbia in 2017. Patients with confirmed TBE were included in the study. Biochemical and serological analysis of blood and CSF, as well as radiological imaging (CT and MRI) were done. Results: In total, 10 patients with TBE were included in the study. M:F ratio was 1.5:1, while average age was 45.1 years. Half of the patients had severe clinical picture. Endocranial CT scan and MRI did not reveal any abnormality, except in the patient with the most severe CNS infection (meningoencephalomyelitis). Mean value of sedimentation and CRP was slightly elevated (29.6 mm/1hours and 20.1 mg/L, respectively) in 80% of the patients, although elevation was almost negligible. The average number of leucocytes in the cerebrospinal fluid (CSF) was 171×106/L, the mean value of the CSF protein was 1.1g/L. There were no fatal outcomes. Conclusion: Since other CNS infections have similar clinical picture and CSF finding as TBE, serological analysis for TBE should be included in routine diagnostic practice. https://jidc.org/index.php/journal/article/view/11516Tick-borne encephalitisSerbiacase-seriesmeningitisencephalitis |
| spellingShingle | Jasmina Poluga Aleksandra Barac Natasa Katanic Salvatore Rubino Branko Milosevic Aleksandar Urosevic Nikola Mitrovic Ivana Kelic Jelena Micic Goran Stevanovic Tick-borne encephalitis in Serbia: A case series Journal of Infection in Developing Countries Tick-borne encephalitis Serbia case-series meningitis encephalitis |
| title | Tick-borne encephalitis in Serbia: A case series |
| title_full | Tick-borne encephalitis in Serbia: A case series |
| title_fullStr | Tick-borne encephalitis in Serbia: A case series |
| title_full_unstemmed | Tick-borne encephalitis in Serbia: A case series |
| title_short | Tick-borne encephalitis in Serbia: A case series |
| title_sort | tick borne encephalitis in serbia a case series |
| topic | Tick-borne encephalitis Serbia case-series meningitis encephalitis |
| url | https://jidc.org/index.php/journal/article/view/11516 |
| work_keys_str_mv | AT jasminapoluga tickborneencephalitisinserbiaacaseseries AT aleksandrabarac tickborneencephalitisinserbiaacaseseries AT natasakatanic tickborneencephalitisinserbiaacaseseries AT salvatorerubino tickborneencephalitisinserbiaacaseseries AT brankomilosevic tickborneencephalitisinserbiaacaseseries AT aleksandarurosevic tickborneencephalitisinserbiaacaseseries AT nikolamitrovic tickborneencephalitisinserbiaacaseseries AT ivanakelic tickborneencephalitisinserbiaacaseseries AT jelenamicic tickborneencephalitisinserbiaacaseseries AT goranstevanovic tickborneencephalitisinserbiaacaseseries |