Understanding therapeutic tolerance through a mathematical model of drug-induced resistance
Abstract There is growing recognition that phenotypic plasticity enables cancer cells to adapt to various environmental conditions. An example of this adaptability is the ability of an initially sensitive population of cancer cells to acquire resistance and persist in the presence of therapeutic age...
Saved in:
| Main Authors: | Jana L. Gevertz, James M. Greene, Samantha Prosperi, Natacha Comandante-Lou, Eduardo D. Sontag |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-025-00511-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Understanding drug resistance in breast cancer: Mechanisms and emerging therapeutic strategies
by: Shreastha Gautam, et al.
Published: (2025-06-01) -
Vitamin D Fortification: A Promising Approach to Overcome Drug Resistance and Tolerance in Therapeutic Interventions
by: null Digvijaya, et al.
Published: (2024-01-01) -
Mathematical models for understanding phenomena: Vortex‐induced vibrations
by: Yukio Tamura
Published: (2020-10-01) -
Treatment strategies for combining immunostimulatory oncolytic virus therapeutics with dendritic cell injections
by: Joanna R. Wares, et al.
Published: (2015-07-01) -
Modeling microbial drug-resistance: from mathematics to pharmacoeconomics
by: Yu. M. Gomon, et al.
Published: (2018-05-01)