Diagnostic Possibilities of Determining the Level of Faecal Calprotectin in Clinical Practice

Aim: to analyze the publications devoted to the modern possibilities of determining the level of faecal calprotectin (FCP) in the diagnosis of various diseases.Key points. In patients with already established diagnosis of inflammatory bowel diseases (IBD), dynamic monitoring of the level of FCP allo...

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Main Authors: A. A. Sheptulin, S. S. Kardasheva, A. A. Kurbatova
Format: Article
Language:Russian
Published: Gastro LLC 2023-05-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/595
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author A. A. Sheptulin
S. S. Kardasheva
A. A. Kurbatova
author_facet A. A. Sheptulin
S. S. Kardasheva
A. A. Kurbatova
author_sort A. A. Sheptulin
collection DOAJ
description Aim: to analyze the publications devoted to the modern possibilities of determining the level of faecal calprotectin (FCP) in the diagnosis of various diseases.Key points. In patients with already established diagnosis of inflammatory bowel diseases (IBD), dynamic monitoring of the level of FCP allows to assess the course and prognosis of the disease, as well as the effectiveness of treatment. The determining of FCP helps in the primary diagnosis of IBD (ulcerative colitis, Crohn's disease, microscopic colitis), contributing to their differentiation from functional bowel disorders, as well as in assessing the course of diverticular intestinal disease and celiac disease. The possibility of using FCP as a marker of colorectal cancer (CRC) and adenomatous polyps of the colon is also discussed.Conclusion. Determining the level of FCP plays an important role in the diagnosis and assessment of the course of a number of gastroenterological diseases (primarily IBD). The significance of FCP as a marker of CRC requires further research.
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spelling doaj-art-060493a40c2f4df5ba046cded2408aad2025-02-10T16:14:37ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732023-05-01326535910.22416/1382-4376-2022-32-6-53-59512Diagnostic Possibilities of Determining the Level of Faecal Calprotectin in Clinical PracticeA. A. Sheptulin0S. S. Kardasheva1A. A. Kurbatova2Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Aim: to analyze the publications devoted to the modern possibilities of determining the level of faecal calprotectin (FCP) in the diagnosis of various diseases.Key points. In patients with already established diagnosis of inflammatory bowel diseases (IBD), dynamic monitoring of the level of FCP allows to assess the course and prognosis of the disease, as well as the effectiveness of treatment. The determining of FCP helps in the primary diagnosis of IBD (ulcerative colitis, Crohn's disease, microscopic colitis), contributing to their differentiation from functional bowel disorders, as well as in assessing the course of diverticular intestinal disease and celiac disease. The possibility of using FCP as a marker of colorectal cancer (CRC) and adenomatous polyps of the colon is also discussed.Conclusion. Determining the level of FCP plays an important role in the diagnosis and assessment of the course of a number of gastroenterological diseases (primarily IBD). The significance of FCP as a marker of CRC requires further research.https://www.gastro-j.ru/jour/article/view/595faecal calprotectininflammatory bowel diseasesfunctional bowel disorderscolorectal cancer
spellingShingle A. A. Sheptulin
S. S. Kardasheva
A. A. Kurbatova
Diagnostic Possibilities of Determining the Level of Faecal Calprotectin in Clinical Practice
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
faecal calprotectin
inflammatory bowel diseases
functional bowel disorders
colorectal cancer
title Diagnostic Possibilities of Determining the Level of Faecal Calprotectin in Clinical Practice
title_full Diagnostic Possibilities of Determining the Level of Faecal Calprotectin in Clinical Practice
title_fullStr Diagnostic Possibilities of Determining the Level of Faecal Calprotectin in Clinical Practice
title_full_unstemmed Diagnostic Possibilities of Determining the Level of Faecal Calprotectin in Clinical Practice
title_short Diagnostic Possibilities of Determining the Level of Faecal Calprotectin in Clinical Practice
title_sort diagnostic possibilities of determining the level of faecal calprotectin in clinical practice
topic faecal calprotectin
inflammatory bowel diseases
functional bowel disorders
colorectal cancer
url https://www.gastro-j.ru/jour/article/view/595
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