Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood
Prenatal diagnosis is an important means of early diagnosis of genetic diseases, which can effectively reduce the risk of birth defects. Free fetal cells, as a carrier of intact fetal genetic material, provide hope for the development of high-sensitivity and high-accuracy prenatal diagnosis technolo...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2022/7131241 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850230944455196672 |
|---|---|
| author | Ying Tang Qiaojin Tang Haiyan Luo Xuehui Zhang Qiuyu Chen Wenying Tang Ting Wang Lihua Yang Hongwu Liao |
| author_facet | Ying Tang Qiaojin Tang Haiyan Luo Xuehui Zhang Qiuyu Chen Wenying Tang Ting Wang Lihua Yang Hongwu Liao |
| author_sort | Ying Tang |
| collection | DOAJ |
| description | Prenatal diagnosis is an important means of early diagnosis of genetic diseases, which can effectively reduce the risk of birth defects. Free fetal cells, as a carrier of intact fetal genetic material, provide hope for the development of high-sensitivity and high-accuracy prenatal diagnosis technology. However, the number of fetal cells is small and it is difficult to apply clinically. In recent years, noninvasive prenatal diagnosis (NIPD) technology for fetal genetic material in maternal peripheral blood has developed rapidly, which makes it possible to diagnose genetic diseases by fetal cells in maternal peripheral blood. This article reviewed the current status of fetal cell separation and enrichment technology and its application in noninvasive prenatal diagnosis technology. |
| format | Article |
| id | doaj-art-05febd8fba724fb89747208a92e308ca |
| institution | OA Journals |
| issn | 2090-9071 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-05febd8fba724fb89747208a92e308ca2025-08-20T02:03:42ZengWileyJournal of Chemistry2090-90712022-01-01202210.1155/2022/7131241Research Progress in Isolation and Enrichment of Fetal Cells from Maternal BloodYing Tang0Qiaojin Tang1Haiyan Luo2Xuehui Zhang3Qiuyu Chen4Wenying Tang5Ting Wang6Lihua Yang7Hongwu Liao8The Affiliated Nanhua HospitalThe Affiliated Nanhua HospitalThe Affiliated Nanhua HospitalThe Hengyang Maternal and Child Health Care HospitalThe Affiliated Nanhua HospitalThe Affiliated Nanhua HospitalThe Affiliated Nanhua HospitalThe Affiliated Hospital of Xiangnan UniversityThe Affiliated Nanhua HospitalPrenatal diagnosis is an important means of early diagnosis of genetic diseases, which can effectively reduce the risk of birth defects. Free fetal cells, as a carrier of intact fetal genetic material, provide hope for the development of high-sensitivity and high-accuracy prenatal diagnosis technology. However, the number of fetal cells is small and it is difficult to apply clinically. In recent years, noninvasive prenatal diagnosis (NIPD) technology for fetal genetic material in maternal peripheral blood has developed rapidly, which makes it possible to diagnose genetic diseases by fetal cells in maternal peripheral blood. This article reviewed the current status of fetal cell separation and enrichment technology and its application in noninvasive prenatal diagnosis technology.http://dx.doi.org/10.1155/2022/7131241 |
| spellingShingle | Ying Tang Qiaojin Tang Haiyan Luo Xuehui Zhang Qiuyu Chen Wenying Tang Ting Wang Lihua Yang Hongwu Liao Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood Journal of Chemistry |
| title | Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood |
| title_full | Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood |
| title_fullStr | Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood |
| title_full_unstemmed | Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood |
| title_short | Research Progress in Isolation and Enrichment of Fetal Cells from Maternal Blood |
| title_sort | research progress in isolation and enrichment of fetal cells from maternal blood |
| url | http://dx.doi.org/10.1155/2022/7131241 |
| work_keys_str_mv | AT yingtang researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood AT qiaojintang researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood AT haiyanluo researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood AT xuehuizhang researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood AT qiuyuchen researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood AT wenyingtang researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood AT tingwang researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood AT lihuayang researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood AT hongwuliao researchprogressinisolationandenrichmentoffetalcellsfrommaternalblood |