Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus
A 72-year-old man presented with a super-refractory partial status epilepticus following evacuation of a right subdural hematoma. He failed to respond to treatment with high doses of intravenous valproic acid, Levetiracetam, Lacosamide, Thiopental, and Midazolam. He was given 4 mg of Perampanel oral...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/8537815 |
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| _version_ | 1832549557402075136 |
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| author | Abdallah Rahbani Grace Adwane Najo Jomaa |
| author_facet | Abdallah Rahbani Grace Adwane Najo Jomaa |
| author_sort | Abdallah Rahbani |
| collection | DOAJ |
| description | A 72-year-old man presented with a super-refractory partial status epilepticus following evacuation of a right subdural hematoma. He failed to respond to treatment with high doses of intravenous valproic acid, Levetiracetam, Lacosamide, Thiopental, and Midazolam. He was given 4 mg of Perampanel orally via nasogastric tube and the dose was rapidly increased to 8 mg after 12 hours with cessation of clinical and electrical seizures. Other antiepileptic drugs were tapered progressively with an excellent clinical outcome. |
| format | Article |
| id | doaj-art-05fcb2cf1c124d0a80e74262d62336ab |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-05fcb2cf1c124d0a80e74262d62336ab2025-02-03T06:10:58ZengWileyCase Reports in Neurological Medicine2090-66682090-66762019-01-01201910.1155/2019/85378158537815Oral Perampanel for the Treatment of Super-Refractory Status EpilepticusAbdallah Rahbani0Grace Adwane1Najo Jomaa2Department of Neurology, Lebanese University, LebanonDepartment of Neurology, Lebanese University, LebanonDepartment of Neurology, Lebanese University, LebanonA 72-year-old man presented with a super-refractory partial status epilepticus following evacuation of a right subdural hematoma. He failed to respond to treatment with high doses of intravenous valproic acid, Levetiracetam, Lacosamide, Thiopental, and Midazolam. He was given 4 mg of Perampanel orally via nasogastric tube and the dose was rapidly increased to 8 mg after 12 hours with cessation of clinical and electrical seizures. Other antiepileptic drugs were tapered progressively with an excellent clinical outcome.http://dx.doi.org/10.1155/2019/8537815 |
| spellingShingle | Abdallah Rahbani Grace Adwane Najo Jomaa Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus Case Reports in Neurological Medicine |
| title | Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus |
| title_full | Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus |
| title_fullStr | Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus |
| title_full_unstemmed | Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus |
| title_short | Oral Perampanel for the Treatment of Super-Refractory Status Epilepticus |
| title_sort | oral perampanel for the treatment of super refractory status epilepticus |
| url | http://dx.doi.org/10.1155/2019/8537815 |
| work_keys_str_mv | AT abdallahrahbani oralperampanelforthetreatmentofsuperrefractorystatusepilepticus AT graceadwane oralperampanelforthetreatmentofsuperrefractorystatusepilepticus AT najojomaa oralperampanelforthetreatmentofsuperrefractorystatusepilepticus |