Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring
In this work 5-methylene-yl - (2-methy –oxazole-4-one) (1H) imidazole (1) were synthesized from the reaction of L-Histidine with acetic anhydride and which converted to the of 5-methylene-yl-(2-methyl 3-amino imidazole-4-one)-1H-imidazole (2) by reaction with hydrazine hydrate. Schiff bases (3-6) we...
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University of Baghdad, College of Science for Women
2016-06-01
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| Series: | مجلة بغداد للعلوم |
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| Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2776 |
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| description | In this work 5-methylene-yl - (2-methy –oxazole-4-one) (1H) imidazole (1) were synthesized from the reaction of L-Histidine with acetic anhydride and which converted to the of 5-methylene-yl-(2-methyl 3-amino imidazole-4-one)-1H-imidazole (2) by reaction with hydrazine hydrate. Schiff bases (3-6) were synthesized from the reaction of compound (2) with different aromatic aldehyde. Reaction of compounds (3-6) with chloroacetyl chloride gives azetidinone one derivatives (7-10). These compounds were characterized by FT-IR and some of them with 1H-NMR and 13C-NMR spectroscopy. |
| format | Article |
| id | doaj-art-05f7da7dc2c645479286ebc331f2ad9e |
| institution | Kabale University |
| issn | 2078-8665 2411-7986 |
| language | English |
| publishDate | 2016-06-01 |
| publisher | University of Baghdad, College of Science for Women |
| record_format | Article |
| series | مجلة بغداد للعلوم |
| spelling | doaj-art-05f7da7dc2c645479286ebc331f2ad9e2025-08-20T03:34:20ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862016-06-0113210.21123/bsj.13.2.307-316Synthesis of New Some Imidazole Derivatives Containing ?-Lactam RingBaghdad Science JournalIn this work 5-methylene-yl - (2-methy –oxazole-4-one) (1H) imidazole (1) were synthesized from the reaction of L-Histidine with acetic anhydride and which converted to the of 5-methylene-yl-(2-methyl 3-amino imidazole-4-one)-1H-imidazole (2) by reaction with hydrazine hydrate. Schiff bases (3-6) were synthesized from the reaction of compound (2) with different aromatic aldehyde. Reaction of compounds (3-6) with chloroacetyl chloride gives azetidinone one derivatives (7-10). These compounds were characterized by FT-IR and some of them with 1H-NMR and 13C-NMR spectroscopy.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2776"L-Histidine, Schiff base, Imidzole." |
| spellingShingle | Baghdad Science Journal Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring مجلة بغداد للعلوم "L-Histidine, Schiff base, Imidzole." |
| title | Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring |
| title_full | Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring |
| title_fullStr | Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring |
| title_full_unstemmed | Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring |
| title_short | Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring |
| title_sort | synthesis of new some imidazole derivatives containing lactam ring |
| topic | "L-Histidine, Schiff base, Imidzole." |
| url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2776 |
| work_keys_str_mv | AT baghdadsciencejournal synthesisofnewsomeimidazolederivativescontaininglactamring |