Comparison of Calibration Drift in Transcutaneous Carbon Dioxide Monitoring Devices for Overnight Level 4 Sleep Study in Hong Kong Children

Background: Level 4 sleep study with transcutaneous carbon dioxide (TcCO2) monitoring is a simple, non-invasive method to investigate sleep-related hypoventilation. However, calibration drift in the TcCO2 device weakens its reliability. Materials and Methods: We conducted a retrospective study of 61...

Full description

Saved in:
Bibliographic Details
Main Authors: Selina Ka-wai Ng, Eric Yat-tung Chan, Shuk-yu Leung
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-04-01
Series:Pediatric Respirology and Critical Care Medicine
Subjects:
Online Access:https://journals.lww.com/10.4103/prcm.prcm_21_23
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849700229167710208
author Selina Ka-wai Ng
Eric Yat-tung Chan
Shuk-yu Leung
author_facet Selina Ka-wai Ng
Eric Yat-tung Chan
Shuk-yu Leung
author_sort Selina Ka-wai Ng
collection DOAJ
description Background: Level 4 sleep study with transcutaneous carbon dioxide (TcCO2) monitoring is a simple, non-invasive method to investigate sleep-related hypoventilation. However, calibration drift in the TcCO2 device weakens its reliability. Materials and Methods: We conducted a retrospective study of 61 patients from <1 to 20 years of age in our paediatric unit, who were assigned one of the two models of TcCO2 machines (SenTec Digital Monitoring System and Tina Radiometer Copenhagen TCM4 Transcutaneous Blood Gas Monitor) for performing the Level 4 sleep study, using capillary blood gas carbon dioxide (pCO2) level at the first and ninth hours as a reference. Results: For the 9-h sleep study, there was no change in the attachment site, membrane, or sensor. The TcCO2–pCO2 difference at the ninth hour in the former model was 0.03 ± 0.61 kPa (0.26 ± 4.59 mm Hg), which was favourable in comparison to the latter (–0.45 ± 1.25 kPa or –3.38 ± 9.38 mm Hg), with P = 0.014; the TcCO2–pCO2 difference between monitors A and B at the ninth hour compared to the first hour did not differ substantially from the former (P = 0.160), but a statistically significant difference was noted in the latter model (P = 0.037). Both findings indicated calibration drift and hence less accurate TcCO2 readings in the latter model. Conclusion: In overnight extended use, calibration drift might affect the diagnosis and management of sleep-related hypoventilation.
format Article
id doaj-art-05ea9f897bff4a7fb30bdf653233d6b3
institution DOAJ
issn 2543-0343
2543-0351
language English
publishDate 2024-04-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Pediatric Respirology and Critical Care Medicine
spelling doaj-art-05ea9f897bff4a7fb30bdf653233d6b32025-08-20T03:18:20ZengWolters Kluwer Medknow PublicationsPediatric Respirology and Critical Care Medicine2543-03432543-03512024-04-0182253210.4103/prcm.prcm_21_23Comparison of Calibration Drift in Transcutaneous Carbon Dioxide Monitoring Devices for Overnight Level 4 Sleep Study in Hong Kong ChildrenSelina Ka-wai NgEric Yat-tung ChanShuk-yu LeungBackground: Level 4 sleep study with transcutaneous carbon dioxide (TcCO2) monitoring is a simple, non-invasive method to investigate sleep-related hypoventilation. However, calibration drift in the TcCO2 device weakens its reliability. Materials and Methods: We conducted a retrospective study of 61 patients from <1 to 20 years of age in our paediatric unit, who were assigned one of the two models of TcCO2 machines (SenTec Digital Monitoring System and Tina Radiometer Copenhagen TCM4 Transcutaneous Blood Gas Monitor) for performing the Level 4 sleep study, using capillary blood gas carbon dioxide (pCO2) level at the first and ninth hours as a reference. Results: For the 9-h sleep study, there was no change in the attachment site, membrane, or sensor. The TcCO2–pCO2 difference at the ninth hour in the former model was 0.03 ± 0.61 kPa (0.26 ± 4.59 mm Hg), which was favourable in comparison to the latter (–0.45 ± 1.25 kPa or –3.38 ± 9.38 mm Hg), with P = 0.014; the TcCO2–pCO2 difference between monitors A and B at the ninth hour compared to the first hour did not differ substantially from the former (P = 0.160), but a statistically significant difference was noted in the latter model (P = 0.037). Both findings indicated calibration drift and hence less accurate TcCO2 readings in the latter model. Conclusion: In overnight extended use, calibration drift might affect the diagnosis and management of sleep-related hypoventilation.https://journals.lww.com/10.4103/prcm.prcm_21_23calibration driftlevel 4 sleep studysleep-disordered breathingsleep-related hypoventilationtranscutaneous carbon dioxide
spellingShingle Selina Ka-wai Ng
Eric Yat-tung Chan
Shuk-yu Leung
Comparison of Calibration Drift in Transcutaneous Carbon Dioxide Monitoring Devices for Overnight Level 4 Sleep Study in Hong Kong Children
Pediatric Respirology and Critical Care Medicine
calibration drift
level 4 sleep study
sleep-disordered breathing
sleep-related hypoventilation
transcutaneous carbon dioxide
title Comparison of Calibration Drift in Transcutaneous Carbon Dioxide Monitoring Devices for Overnight Level 4 Sleep Study in Hong Kong Children
title_full Comparison of Calibration Drift in Transcutaneous Carbon Dioxide Monitoring Devices for Overnight Level 4 Sleep Study in Hong Kong Children
title_fullStr Comparison of Calibration Drift in Transcutaneous Carbon Dioxide Monitoring Devices for Overnight Level 4 Sleep Study in Hong Kong Children
title_full_unstemmed Comparison of Calibration Drift in Transcutaneous Carbon Dioxide Monitoring Devices for Overnight Level 4 Sleep Study in Hong Kong Children
title_short Comparison of Calibration Drift in Transcutaneous Carbon Dioxide Monitoring Devices for Overnight Level 4 Sleep Study in Hong Kong Children
title_sort comparison of calibration drift in transcutaneous carbon dioxide monitoring devices for overnight level 4 sleep study in hong kong children
topic calibration drift
level 4 sleep study
sleep-disordered breathing
sleep-related hypoventilation
transcutaneous carbon dioxide
url https://journals.lww.com/10.4103/prcm.prcm_21_23
work_keys_str_mv AT selinakawaing comparisonofcalibrationdriftintranscutaneouscarbondioxidemonitoringdevicesforovernightlevel4sleepstudyinhongkongchildren
AT ericyattungchan comparisonofcalibrationdriftintranscutaneouscarbondioxidemonitoringdevicesforovernightlevel4sleepstudyinhongkongchildren
AT shukyuleung comparisonofcalibrationdriftintranscutaneouscarbondioxidemonitoringdevicesforovernightlevel4sleepstudyinhongkongchildren