Prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population: 10 year follow-up

The aim of this study was to investigate the prevalence and seasonal distribution of respiratory viruses in pediatric patients. Nasopharyngeal swab specimens, demographic and clinical information were collected from 1240 pediatric patients aged < 18 years between 2006 and 2015 in Hacettepe Unive...

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Main Authors: Kübra Aykaç, Ateş Kara, Ali Bülent Cengiz, Alpaslan Alp, Yasemin Özsürekci, Mustafa Şenol Akın, Sevgen Tanır-Başaranoğlu, Cihangül Bayhan, Eda Karadağ-Öncel, Mehmet Ceyhan
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2018-12-01
Series:The Turkish Journal of Pediatrics
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Online Access:https://turkjpediatr.org/article/view/918
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author Kübra Aykaç
Ateş Kara
Ali Bülent Cengiz
Alpaslan Alp
Yasemin Özsürekci
Mustafa Şenol Akın
Sevgen Tanır-Başaranoğlu
Cihangül Bayhan
Eda Karadağ-Öncel
Mehmet Ceyhan
author_facet Kübra Aykaç
Ateş Kara
Ali Bülent Cengiz
Alpaslan Alp
Yasemin Özsürekci
Mustafa Şenol Akın
Sevgen Tanır-Başaranoğlu
Cihangül Bayhan
Eda Karadağ-Öncel
Mehmet Ceyhan
author_sort Kübra Aykaç
collection DOAJ
description The aim of this study was to investigate the prevalence and seasonal distribution of respiratory viruses in pediatric patients. Nasopharyngeal swab specimens, demographic and clinical information were collected from 1240 pediatric patients aged < 18 years between 2006 and 2015 in Hacettepe University Children`s Hospital. Multiplex RT-PCR (multiplex reverse transcriptase polymerase chain reaction) was performed to detect viral pathogens. A total of 1240 pediatric outpatients and inpatients who had been admitted to the hospital with symptoms of upper and lower respiratory tract infections (RTIs) were enrolled. Viruses were identified in 339 (27.3%) of cases, with the leading three viruses being respiratory syncytial virus (RSV, 74/339; 21.8%), human rhinovirus (62/339; 18.3%), and multiple viruses (56/339; 16.5%). Most of the patients were diagnosed with lower RTI (264/339; 77.8%) and antibiotics were administered to three quarters of positive patients (254/339; 74.9%). With an overall viral agent detection rate of 27.3%, the findings of the present study suggest that other respiratory pathogens, whether viral or bacterial, may also lead to hospital visits due to respiratory tract symptoms in children.
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publisher Hacettepe University Institute of Child Health
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series The Turkish Journal of Pediatrics
spelling doaj-art-05e70cd281d64e4faa6adbcb48a239a42025-08-20T02:01:47ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212018-12-0160610.24953/turkjped.2018.06.004Prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population: 10 year follow-upKübra Aykaç0Ateş Kara1Ali Bülent Cengiz2Alpaslan Alp3Yasemin Özsürekci4Mustafa Şenol Akın5Sevgen Tanır-Başaranoğlu6Cihangül Bayhan7Eda Karadağ-Öncel8Mehmet Ceyhan9Division of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.Department of Microbiology and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey.Division of Pediatric Infectious Diseases, Hacettepe University Faculty of Medicine, Ankara, Turkey. The aim of this study was to investigate the prevalence and seasonal distribution of respiratory viruses in pediatric patients. Nasopharyngeal swab specimens, demographic and clinical information were collected from 1240 pediatric patients aged < 18 years between 2006 and 2015 in Hacettepe University Children`s Hospital. Multiplex RT-PCR (multiplex reverse transcriptase polymerase chain reaction) was performed to detect viral pathogens. A total of 1240 pediatric outpatients and inpatients who had been admitted to the hospital with symptoms of upper and lower respiratory tract infections (RTIs) were enrolled. Viruses were identified in 339 (27.3%) of cases, with the leading three viruses being respiratory syncytial virus (RSV, 74/339; 21.8%), human rhinovirus (62/339; 18.3%), and multiple viruses (56/339; 16.5%). Most of the patients were diagnosed with lower RTI (264/339; 77.8%) and antibiotics were administered to three quarters of positive patients (254/339; 74.9%). With an overall viral agent detection rate of 27.3%, the findings of the present study suggest that other respiratory pathogens, whether viral or bacterial, may also lead to hospital visits due to respiratory tract symptoms in children. https://turkjpediatr.org/article/view/918childrenrespiratory infectionsviruses
spellingShingle Kübra Aykaç
Ateş Kara
Ali Bülent Cengiz
Alpaslan Alp
Yasemin Özsürekci
Mustafa Şenol Akın
Sevgen Tanır-Başaranoğlu
Cihangül Bayhan
Eda Karadağ-Öncel
Mehmet Ceyhan
Prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population: 10 year follow-up
The Turkish Journal of Pediatrics
children
respiratory infections
viruses
title Prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population: 10 year follow-up
title_full Prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population: 10 year follow-up
title_fullStr Prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population: 10 year follow-up
title_full_unstemmed Prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population: 10 year follow-up
title_short Prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population: 10 year follow-up
title_sort prevalence and seasonal distribution of viral etiology of respiratory tract infections in inpatients and outpatients of the pediatric population 10 year follow up
topic children
respiratory infections
viruses
url https://turkjpediatr.org/article/view/918
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