Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast Cancer

<b>Background/Objectives:</b> Higher percent body fat (BF) is associated with worse outcomes after treatment for breast cancer (BC). While ultrasound (US) imaging is a reliable method for analyzing body composition, it requires trained individuals for utilization. As such, bioelectrical...

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Main Authors: Jared Rosenberg, Jyotsna Natarajan, David J. Carpenter, Chris Peluso, Christie Hilton, Colin E. Champ
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/12/1545
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author Jared Rosenberg
Jyotsna Natarajan
David J. Carpenter
Chris Peluso
Christie Hilton
Colin E. Champ
author_facet Jared Rosenberg
Jyotsna Natarajan
David J. Carpenter
Chris Peluso
Christie Hilton
Colin E. Champ
author_sort Jared Rosenberg
collection DOAJ
description <b>Background/Objectives:</b> Higher percent body fat (BF) is associated with worse outcomes after treatment for breast cancer (BC). While ultrasound (US) imaging is a reliable method for analyzing body composition, it requires trained individuals for utilization. As such, bioelectrical impedance analysis (BIA) has been suggested as an alternative. Therefore, the goal of this study was to compare BIA with US. <b>Methods</b>: Women from three prospective exercise BC studies were analyzed with US and BIA before an exercise intervention. Spearman’s correlation was used as a nonparametric measure to examine bivariate relationships between percent body fat measured by BIA and US. <b>Results</b>: In total, 106 women with BC had their body composition measured using both US and BIA. Despite a strong correlation between the two methods (r = 0.8, <i>p</i> < 0.01), US reported lower mean percent BF vs. BIA (34.6 ± 0.7% vs. 38.0 ± 0.8%, <i>p</i> < 0.01). In a subgroup analysis, concordance was seen in women with a body mass index below (BMI) ≤ 26 kg/m<sup>2</sup>. BIA overreported percent BF compared to US in women with a BMI > 26 kg/m<sup>2</sup>. <b>Conclusions</b>: In women with BC and BMI ≤ 26, US and BIA are in concordance when measuring BF. In women with a BMI > 26, BIA reports a higher BF than US. Overall, there was a strong correlation between modalities, while BMI can be used to guide the utilization of BIA as an alternative to US for assessing body composition.
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spelling doaj-art-05bc9754c97b4c5da422b3362a51b4812025-08-20T03:27:21ZengMDPI AGDiagnostics2075-44182025-06-011512154510.3390/diagnostics15121545Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast CancerJared Rosenberg0Jyotsna Natarajan1David J. Carpenter2Chris Peluso3Christie Hilton4Colin E. Champ5Kinesiology Department, SUNY Cortland, Cortland, NY 13045, USADrexel University College of Medicine, Philadelphia, PA 19129, USAExercise Oncology Consortium, Pittsburgh, PA 15232, USAExercise Oncology Consortium, Pittsburgh, PA 15232, USADepartment of Medical Oncology, Allegheny Health Network, Pittsburgh, PA 15212, USAExercise Oncology Consortium, Pittsburgh, PA 15232, USA<b>Background/Objectives:</b> Higher percent body fat (BF) is associated with worse outcomes after treatment for breast cancer (BC). While ultrasound (US) imaging is a reliable method for analyzing body composition, it requires trained individuals for utilization. As such, bioelectrical impedance analysis (BIA) has been suggested as an alternative. Therefore, the goal of this study was to compare BIA with US. <b>Methods</b>: Women from three prospective exercise BC studies were analyzed with US and BIA before an exercise intervention. Spearman’s correlation was used as a nonparametric measure to examine bivariate relationships between percent body fat measured by BIA and US. <b>Results</b>: In total, 106 women with BC had their body composition measured using both US and BIA. Despite a strong correlation between the two methods (r = 0.8, <i>p</i> < 0.01), US reported lower mean percent BF vs. BIA (34.6 ± 0.7% vs. 38.0 ± 0.8%, <i>p</i> < 0.01). In a subgroup analysis, concordance was seen in women with a body mass index below (BMI) ≤ 26 kg/m<sup>2</sup>. BIA overreported percent BF compared to US in women with a BMI > 26 kg/m<sup>2</sup>. <b>Conclusions</b>: In women with BC and BMI ≤ 26, US and BIA are in concordance when measuring BF. In women with a BMI > 26, BIA reports a higher BF than US. Overall, there was a strong correlation between modalities, while BMI can be used to guide the utilization of BIA as an alternative to US for assessing body composition.https://www.mdpi.com/2075-4418/15/12/1545ultrasoundbioelectrical impedance analysiscancerbody composition
spellingShingle Jared Rosenberg
Jyotsna Natarajan
David J. Carpenter
Chris Peluso
Christie Hilton
Colin E. Champ
Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast Cancer
Diagnostics
ultrasound
bioelectrical impedance analysis
cancer
body composition
title Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast Cancer
title_full Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast Cancer
title_fullStr Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast Cancer
title_full_unstemmed Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast Cancer
title_short Agreement Between Bioelectrical Impedance Analysis and Ultrasound for Measuring Body Composition in Women with Breast Cancer
title_sort agreement between bioelectrical impedance analysis and ultrasound for measuring body composition in women with breast cancer
topic ultrasound
bioelectrical impedance analysis
cancer
body composition
url https://www.mdpi.com/2075-4418/15/12/1545
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