NETosis-based prognostic model reveals immune modulation in clear cell renal cell carcinoma using single-cell and bulk RNA sequencing

NETosis-based prognostic model reveals immune modulation in clear cell renal cell carcinoma using single-cell and bulk RNA sequencing

Abstract Further research is needed to investigate the association between netosis and clear cell renal cell carcinoma (ccRCC). We developed a prognostic framework for netosis using univariate, Lasso, and multivariate Cox regression analyses. The CIBERSORT algorithm was employed to compute immune in...

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Bibliographic Details
Main Authors: Zijie Yu, Zihao Xu, Xi Zhang, Wenchuan Shao, Da Zhong, Xinghan Yan, Tingfei Jiang, Yichun Wang, Ninghong Song
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Single-cell RNA sequencing
Bulk RNA sequencing
Clear cell renal cell carcinoma
Immune environment
Prognostic model
Online Access:https://doi.org/10.1038/s41598-025-11095-7
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