Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma

Background. Hepatic angiosarcoma is a rare and aggressive tumor that often presents at an advanced stage with nonspecific symptoms. Objective. To report a case of primary hepatic angiosarcoma in an otherwise healthy man with normal liver function tests two months prior to presenting with a short per...

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Main Authors: Ayokunle T. Abegunde, Efe Aisien, Benjamin Mba, Rohini Chennuri, Marin Sekosan
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2015/869746
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author Ayokunle T. Abegunde
Efe Aisien
Benjamin Mba
Rohini Chennuri
Marin Sekosan
author_facet Ayokunle T. Abegunde
Efe Aisien
Benjamin Mba
Rohini Chennuri
Marin Sekosan
author_sort Ayokunle T. Abegunde
collection DOAJ
description Background. Hepatic angiosarcoma is a rare and aggressive tumor that often presents at an advanced stage with nonspecific symptoms. Objective. To report a case of primary hepatic angiosarcoma in an otherwise healthy man with normal liver function tests two months prior to presenting with a short period of jaundice that progressed to fulminant hepatic failure. Methods. Case report and review of literature. Conclusion. This case illustrates the rapidity of progression to death after the onset of symptoms in a patient with hepatic angiosarcoma. Research on early diagnostic strategies and newer therapies are needed to improve prognosis in this rare and poorly understood malignancy with limited treatment options.
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publishDate 2015-01-01
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-059ce2f9fe9a45e88781bab38eb2f5d52025-08-20T02:02:58ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362015-01-01201510.1155/2015/869746869746Fulminant Hepatic Failure Secondary to Primary Hepatic AngiosarcomaAyokunle T. Abegunde0Efe Aisien1Benjamin Mba2Rohini Chennuri3Marin Sekosan4Department of Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, IL 60612, USADepartment of Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, IL 60612, USADepartment of Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, IL 60612, USADepartment of Pathology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL 60612, USADepartment of Pathology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL 60612, USABackground. Hepatic angiosarcoma is a rare and aggressive tumor that often presents at an advanced stage with nonspecific symptoms. Objective. To report a case of primary hepatic angiosarcoma in an otherwise healthy man with normal liver function tests two months prior to presenting with a short period of jaundice that progressed to fulminant hepatic failure. Methods. Case report and review of literature. Conclusion. This case illustrates the rapidity of progression to death after the onset of symptoms in a patient with hepatic angiosarcoma. Research on early diagnostic strategies and newer therapies are needed to improve prognosis in this rare and poorly understood malignancy with limited treatment options.http://dx.doi.org/10.1155/2015/869746
spellingShingle Ayokunle T. Abegunde
Efe Aisien
Benjamin Mba
Rohini Chennuri
Marin Sekosan
Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma
Case Reports in Gastrointestinal Medicine
title Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma
title_full Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma
title_fullStr Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma
title_full_unstemmed Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma
title_short Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma
title_sort fulminant hepatic failure secondary to primary hepatic angiosarcoma
url http://dx.doi.org/10.1155/2015/869746
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AT benjaminmba fulminanthepaticfailuresecondarytoprimaryhepaticangiosarcoma
AT rohinichennuri fulminanthepaticfailuresecondarytoprimaryhepaticangiosarcoma
AT marinsekosan fulminanthepaticfailuresecondarytoprimaryhepaticangiosarcoma