Iatrogenic Hyperkalemia Induced by Hypermagnesemia From Administration of Laxatives in a Patient With Gastroparesis

Magnesium-containing drugs such as magnesium citrate are popular over-the-counter laxatives used to treat constipation. Although generally well tolerated, excessive intake can result in potentially dangerous electrolyte abnormalities. Of these abnormalities, hyperkalemia is one that is heavily under...

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Bibliographic Details
Main Authors: Hafez Golzarian, Morgan Turnow, Sidney Elston, Alaha Mariam, Sidra Shah, Syed H. Haq, Benjamin Pasley, Chris Hawkins, Jayde E. Kurland
Format: Article
Language:English
Published: American College of Physicians 2022-10-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.0634
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Summary:Magnesium-containing drugs such as magnesium citrate are popular over-the-counter laxatives used to treat constipation. Although generally well tolerated, excessive intake can result in potentially dangerous electrolyte abnormalities. Of these abnormalities, hyperkalemia is one that is heavily underreported. We report an elderly woman who presented for gastroparesis flare-up and constipation. She was given magnesium citrate and subsequently developed hypermagnesemia, which resulted in hyperkalemia. By presenting this case, we hope to increase awareness of this heavily underreported side effect of magnesium-based laxatives, especially in the setting of gastrointestinal disturbances that may affect the absorption of these electrolytes.
ISSN:2767-7664