Prediction of influenza A virus-human protein-protein interactions using XGBoost with continuous and discontinuous amino acids information

Prediction of influenza A virus-human protein-protein interactions using XGBoost with continuous and discontinuous amino acids information

Influenza A virus (IAV) has the characteristics of high infectivity and high pathogenicity, which makes IAV infection a serious public health threat. Identifying protein-protein interactions (PPIs) between IAV and human proteins is beneficial for understanding the mechanism of viral infection and de...

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Bibliographic Details
Main Authors: Binghua Li, Xin Li, Xiaoyu Li, Li Wang, Jun Lu, Jia Wang
Format: Article
Language:English
Published: PeerJ Inc. 2025-01-01
Series:PeerJ
Subjects:
Pathogen-host interaction (PHI)
Protein-protein interaction (PPI)
Influenza A virus
XGBoost
Machine learning
GO and KEGG
Online Access:https://peerj.com/articles/18863.pdf
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