A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and Management

A 26-year-old male without any significant past medical history presented to the hospital with shortness of breath, cough, pleuritic chest pain, and weight loss for the past 3 months. On chest CT, he was found to have extensive mediastinal and hilar lymphadenopathy and multiple pulmonary nodules. On...

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Main Authors: Shahzaib Nabi, Abhijit Saste, Rohit Gulati
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2015/925453
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author Shahzaib Nabi
Abhijit Saste
Rohit Gulati
author_facet Shahzaib Nabi
Abhijit Saste
Rohit Gulati
author_sort Shahzaib Nabi
collection DOAJ
description A 26-year-old male without any significant past medical history presented to the hospital with shortness of breath, cough, pleuritic chest pain, and weight loss for the past 3 months. On chest CT, he was found to have extensive mediastinal and hilar lymphadenopathy and multiple pulmonary nodules. On physical examination, a right groin mass was noted which had been slowly growing for the past 2 years. Ultrasound of the groin showed complex solid mass with internal vascular channels. CT guided biopsy of the mass showed desmoplastic small round cell tumour. His hospital course was complicated by hypoxic respiratory failure requiring emergent intubation and ICU admission where he completed one cycle of vincristine, cyclophosphamide, and doxorubicin with subsequent improvement, followed by extubation. His condition continued to improve after second cycle of chemotherapy and he was ultimately discharged in a stable condition to continue outpatient chemotherapy after a 2-month inpatient stay.
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issn 2090-6706
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series Case Reports in Oncological Medicine
spelling doaj-art-0577c4f9614a4e43b17e0c1045f9e9812025-02-03T01:07:48ZengWileyCase Reports in Oncological Medicine2090-67062090-67142015-01-01201510.1155/2015/925453925453A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and ManagementShahzaib Nabi0Abhijit Saste1Rohit Gulati2Department of Internal Medicine, Henry Ford Health System, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Hematology-Oncology, Henry Ford Health System, 2799 W. Grand Boulevard, Detroit, MI 48202, USADepartment of Pathology, Henry Ford Health System, 2799 W. Grand Boulevard, Detroit, MI 48202, USAA 26-year-old male without any significant past medical history presented to the hospital with shortness of breath, cough, pleuritic chest pain, and weight loss for the past 3 months. On chest CT, he was found to have extensive mediastinal and hilar lymphadenopathy and multiple pulmonary nodules. On physical examination, a right groin mass was noted which had been slowly growing for the past 2 years. Ultrasound of the groin showed complex solid mass with internal vascular channels. CT guided biopsy of the mass showed desmoplastic small round cell tumour. His hospital course was complicated by hypoxic respiratory failure requiring emergent intubation and ICU admission where he completed one cycle of vincristine, cyclophosphamide, and doxorubicin with subsequent improvement, followed by extubation. His condition continued to improve after second cycle of chemotherapy and he was ultimately discharged in a stable condition to continue outpatient chemotherapy after a 2-month inpatient stay.http://dx.doi.org/10.1155/2015/925453
spellingShingle Shahzaib Nabi
Abhijit Saste
Rohit Gulati
A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and Management
Case Reports in Oncological Medicine
title A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and Management
title_full A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and Management
title_fullStr A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and Management
title_full_unstemmed A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and Management
title_short A Rare Case of Metastatic Desmoplastic Small Round Cell Tumour: Diagnosis and Management
title_sort rare case of metastatic desmoplastic small round cell tumour diagnosis and management
url http://dx.doi.org/10.1155/2015/925453
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