Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriers

Objectives The widespread adoption of wearables, for example, smartphones and smartwatches in the daily lives of the general population, allows passive monitoring of physiological and behavioural data in the real world. This qualitative study explores the perspective of psoriatic arthritis (PsA) pat...

Full description

Saved in:
Bibliographic Details
Main Authors: Ilja Tchetverikov, Marijn Vis, Marc R. Kok, Jolanda J. Luime, Yvonne P.M. Goekoop-Ruiterman, Wendy Wagenaar, Laura C. Coates, Patty de Groot, Jasper Foolen
Format: Article
Language:English
Published: BMJ Publishing Group 2024-12-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/10/4/e004699.full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850065336467980288
author Ilja Tchetverikov
Marijn Vis
Marc R. Kok
Jolanda J. Luime
Yvonne P.M. Goekoop-Ruiterman
Wendy Wagenaar
Laura C. Coates
Patty de Groot
Jasper Foolen
author_facet Ilja Tchetverikov
Marijn Vis
Marc R. Kok
Jolanda J. Luime
Yvonne P.M. Goekoop-Ruiterman
Wendy Wagenaar
Laura C. Coates
Patty de Groot
Jasper Foolen
author_sort Ilja Tchetverikov
collection DOAJ
description Objectives The widespread adoption of wearables, for example, smartphones and smartwatches in the daily lives of the general population, allows passive monitoring of physiological and behavioural data in the real world. This qualitative study explores the perspective of psoriatic arthritis (PsA) patients towards these so-called digital biomarkers (dBMs).Methods As part of a Design Thinking approach, six focus groups were conducted involving 27 PsA patients. The semistructured topic guide included disease activity, coping strategies, care needs, and potential advantages and disadvantages of dBMs. Thematic analysis followed an abductive coding method.Results PsA daily permeates patients’ lives, both physically and mentally. Participants discussed how their lives are focused on minimising the impact of the disease on their daily routines. Their attempts to gain control over their disease highly depend on trial and error. Flare-ups are related to physiological as well as behavioural micro and macro changes. Understanding these changes could enable the detection of (early) flare. Participants elicited pros and cons of the use of dBMs, discussed their intended use and made practical remarks. This led to three main themes: ‘Perceived dBM opportunities’, ‘Mapping Disease activity’ and ‘Perceived dBM barriers and pitfalls’.Conclusion PsA patients are receptive to dBMs for tracking the disease symptoms. Disease activity is regarded multifaceted and thus, dBMs should include a broad range of features to truly reflect the disease activity status. Reducing the time of trial and error in learning to manage the disease is regarded beneficial. Establishing and maintaining the relationship with their attending physicians is a prerequisite, even if remote patient monitoring becomes an alternative for some physical hospital visits.
format Article
id doaj-art-0575a0511ecb439bb3d80f6c650a0a88
institution DOAJ
issn 2056-5933
language English
publishDate 2024-12-01
publisher BMJ Publishing Group
record_format Article
series RMD Open
spelling doaj-art-0575a0511ecb439bb3d80f6c650a0a882025-08-20T02:49:02ZengBMJ Publishing GroupRMD Open2056-59332024-12-0110410.1136/rmdopen-2024-004699Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriersIlja Tchetverikov0Marijn Vis1Marc R. Kok2Jolanda J. Luime3Yvonne P.M. Goekoop-Ruiterman4Wendy Wagenaar5Laura C. Coates6Patty de Groot7Jasper Foolen8Department of Rheumatology, Albert Schweitzer Hospital, Dordrecht, Zuid-Holland, The NetherlandsDepartment of Rheumatology, Erasmus MC, Rotterdam, Zuid-Holland, The NetherlandsDepartment of Rheumatology and Clinical Immunology, Maasstad Hospital, Rotterdam, Zuid-Holland, The NetherlandsDepartment of Rheumatology, Erasmus MC, Rotterdam, Zuid-Holland, The NetherlandsDepartment of Rheumatology, Haga Hospital, Den Haag, Zuid-Holland, The NetherlandsTranzo, Tilburg University, Tilburg, Noord-Brabant, The NetherlandsNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UKDepartment of Rheumatology, Erasmus MC, Rotterdam, Zuid-Holland, The NetherlandsDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Noord-Brabant, The NetherlandsObjectives The widespread adoption of wearables, for example, smartphones and smartwatches in the daily lives of the general population, allows passive monitoring of physiological and behavioural data in the real world. This qualitative study explores the perspective of psoriatic arthritis (PsA) patients towards these so-called digital biomarkers (dBMs).Methods As part of a Design Thinking approach, six focus groups were conducted involving 27 PsA patients. The semistructured topic guide included disease activity, coping strategies, care needs, and potential advantages and disadvantages of dBMs. Thematic analysis followed an abductive coding method.Results PsA daily permeates patients’ lives, both physically and mentally. Participants discussed how their lives are focused on minimising the impact of the disease on their daily routines. Their attempts to gain control over their disease highly depend on trial and error. Flare-ups are related to physiological as well as behavioural micro and macro changes. Understanding these changes could enable the detection of (early) flare. Participants elicited pros and cons of the use of dBMs, discussed their intended use and made practical remarks. This led to three main themes: ‘Perceived dBM opportunities’, ‘Mapping Disease activity’ and ‘Perceived dBM barriers and pitfalls’.Conclusion PsA patients are receptive to dBMs for tracking the disease symptoms. Disease activity is regarded multifaceted and thus, dBMs should include a broad range of features to truly reflect the disease activity status. Reducing the time of trial and error in learning to manage the disease is regarded beneficial. Establishing and maintaining the relationship with their attending physicians is a prerequisite, even if remote patient monitoring becomes an alternative for some physical hospital visits.https://rmdopen.bmj.com/content/10/4/e004699.full
spellingShingle Ilja Tchetverikov
Marijn Vis
Marc R. Kok
Jolanda J. Luime
Yvonne P.M. Goekoop-Ruiterman
Wendy Wagenaar
Laura C. Coates
Patty de Groot
Jasper Foolen
Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriers
RMD Open
title Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriers
title_full Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriers
title_fullStr Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriers
title_full_unstemmed Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriers
title_short Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriers
title_sort digital biomarkers for psoriatic arthritis a qualitative focus group study on patient perceived opportunities and barriers
url https://rmdopen.bmj.com/content/10/4/e004699.full
work_keys_str_mv AT iljatchetverikov digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers
AT marijnvis digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers
AT marcrkok digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers
AT jolandajluime digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers
AT yvonnepmgoekoopruiterman digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers
AT wendywagenaar digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers
AT lauraccoates digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers
AT pattydegroot digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers
AT jasperfoolen digitalbiomarkersforpsoriaticarthritisaqualitativefocusgroupstudyonpatientperceivedopportunitiesandbarriers