Colopathy associated with pentosan polysulfate use

Colopathy associated with pentosan polysulfate use

IntroductionWe describe a novel colopathy associated with pentosan polysulfate (PPS) use and assess the strength of the drug-disease association in a two-part investigation.Methods1. Cohort Study: We studied individuals with a history of long-term PPS use. Case histories concerning gastrointestinal...

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Bibliographic Details
Main Authors: Emily H. Jung, Wei Zheng, Ryan J. Weiss, Namita E. Mathew, Benjamin I. Meyer, Azhar Nizam, Heba Iskandar, Nieraj Jain
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
pentosan polysulfate
elmiron
interstitial cystitis
inflammatory bowel disease
irritable bowel syndrome
toxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1494467/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1494467/full

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