Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations

Humans are exposed to metals through diet and lifestyle e.g. smoking. Some metals are essential for physiologically body functions, while others are non-essential and can be toxic to humans. This study follows up on metal concentrations in the Greenlandic ACCEPT birth-cohort (mothers and fathers) an...

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Main Authors: Maria Wielsøe, Manhai Long, Jens Søndergaard, Eva Cecilie Bonefeld-Jørgensen
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:International Journal of Circumpolar Health
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Online Access:https://www.tandfonline.com/doi/10.1080/22423982.2024.2381308
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author Maria Wielsøe
Manhai Long
Jens Søndergaard
Eva Cecilie Bonefeld-Jørgensen
author_facet Maria Wielsøe
Manhai Long
Jens Søndergaard
Eva Cecilie Bonefeld-Jørgensen
author_sort Maria Wielsøe
collection DOAJ
description Humans are exposed to metals through diet and lifestyle e.g. smoking. Some metals are essential for physiologically body functions, while others are non-essential and can be toxic to humans. This study follows up on metal concentrations in the Greenlandic ACCEPT birth-cohort (mothers and fathers) and compares with other Arctic populations. The data from 2019 to 2020 include blood metal concentrations, lifestyle and food frequency questionnaires from 101 mothers and 76 fathers, 24–55 years, living in Nuuk, Sisimiut, and Ilulissat. A high percentage (25–45%) exceeded international guidance values for Hg. For the mothers, the metal concentrations changed significantly from inclusion at pregnancy to this follow-up 3–5 years after birth; some increased and others decreased. Most metals differed significantly between mothers and fathers, while few also differed between residential towns. Several metals correlated significantly with marine food intake and socio-economic factors, but the direction of the correlations varied. Traditional marine food intake was associated positively with Se, As and Hg. To the best of our knowledge, this study provides the most recent data on metal exposure of both men and women in Greenland, elucidating metal exposure sources among Arctic populations, and documents the need for continuing biomonitoring to follow the exceeding of guidance values for Hg. [Figure: see text]
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publishDate 2024-12-01
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series International Journal of Circumpolar Health
spelling doaj-art-054d6b6548a44024aeb9bc3f436b02c52025-08-20T02:49:06ZengTaylor & Francis GroupInternational Journal of Circumpolar Health2242-39822024-12-0183110.1080/22423982.2024.2381308Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populationsMaria Wielsøe0Manhai Long1Jens Søndergaard2Eva Cecilie Bonefeld-Jørgensen3Centre for Arctic Health & Molecular Epidemiology, Department of Public Health, Aarhus University, Aarhus, DenmarkCentre for Arctic Health & Molecular Epidemiology, Department of Public Health, Aarhus University, Aarhus, DenmarkDepartment of Ecoscience, Aarhus University, Roskilde, DenmarkCentre for Arctic Health & Molecular Epidemiology, Department of Public Health, Aarhus University, Aarhus, DenmarkHumans are exposed to metals through diet and lifestyle e.g. smoking. Some metals are essential for physiologically body functions, while others are non-essential and can be toxic to humans. This study follows up on metal concentrations in the Greenlandic ACCEPT birth-cohort (mothers and fathers) and compares with other Arctic populations. The data from 2019 to 2020 include blood metal concentrations, lifestyle and food frequency questionnaires from 101 mothers and 76 fathers, 24–55 years, living in Nuuk, Sisimiut, and Ilulissat. A high percentage (25–45%) exceeded international guidance values for Hg. For the mothers, the metal concentrations changed significantly from inclusion at pregnancy to this follow-up 3–5 years after birth; some increased and others decreased. Most metals differed significantly between mothers and fathers, while few also differed between residential towns. Several metals correlated significantly with marine food intake and socio-economic factors, but the direction of the correlations varied. Traditional marine food intake was associated positively with Se, As and Hg. To the best of our knowledge, this study provides the most recent data on metal exposure of both men and women in Greenland, elucidating metal exposure sources among Arctic populations, and documents the need for continuing biomonitoring to follow the exceeding of guidance values for Hg. [Figure: see text]https://www.tandfonline.com/doi/10.1080/22423982.2024.2381308Essential metalsheavy metalsseleniumleadmercurycadmium
spellingShingle Maria Wielsøe
Manhai Long
Jens Søndergaard
Eva Cecilie Bonefeld-Jørgensen
Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations
International Journal of Circumpolar Health
Essential metals
heavy metals
selenium
lead
mercury
cadmium
title Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations
title_full Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations
title_fullStr Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations
title_full_unstemmed Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations
title_short Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations
title_sort metal exposure in the greenlandic accept cohort follow up and comparison with other arctic populations
topic Essential metals
heavy metals
selenium
lead
mercury
cadmium
url https://www.tandfonline.com/doi/10.1080/22423982.2024.2381308
work_keys_str_mv AT mariawielsøe metalexposureinthegreenlandicacceptcohortfollowupandcomparisonwithotherarcticpopulations
AT manhailong metalexposureinthegreenlandicacceptcohortfollowupandcomparisonwithotherarcticpopulations
AT jenssøndergaard metalexposureinthegreenlandicacceptcohortfollowupandcomparisonwithotherarcticpopulations
AT evaceciliebonefeldjørgensen metalexposureinthegreenlandicacceptcohortfollowupandcomparisonwithotherarcticpopulations