The accuracy of the Hounsfield unit in pulmonary embolism diagnostics

Objective Pulmonary embolism (PE) is a vascular disease that is most frequently diagnosed using the radiological imaging technique computed tomography pulmonary angiography (CTPA). In this study, we aimed to demonstrate the diagnostic accuracy of the Hounsfield unit (HU) for PE based on the hypothes...

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Main Authors: Mümin Murat Yazici, Sümeyye Sekmen, Ali Çelik, Özcan Yavaşi, Nur Hürsoy
Format: Article
Language:English
Published: The Korean Society of Emergency Medicine 2024-09-01
Series:Clinical and Experimental Emergency Medicine
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Online Access:http://www.ceemjournal.org/upload/pdf/ceem-23-113.pdf
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author Mümin Murat Yazici
Sümeyye Sekmen
Ali Çelik
Özcan Yavaşi
Nur Hürsoy
author_facet Mümin Murat Yazici
Sümeyye Sekmen
Ali Çelik
Özcan Yavaşi
Nur Hürsoy
author_sort Mümin Murat Yazici
collection DOAJ
description Objective Pulmonary embolism (PE) is a vascular disease that is most frequently diagnosed using the radiological imaging technique computed tomography pulmonary angiography (CTPA). In this study, we aimed to demonstrate the diagnostic accuracy of the Hounsfield unit (HU) for PE based on the hypothesis that acute thrombosis causes an increase in HU value on CT. Methods This research was a single-center, retrospective study. Patients presenting to the emergency department diagnosed with PE on CTPA were enrolled as the study group. Patients admitted to the same emergency department who were not diagnosed with PE and had noncontrast CT scans were included as the control group. A receiver operating curve was produced to determine the diagnostic accuracy of HU values in predicting PE. Results The study population (n=74) consisted of a study group (n=46) and a control group (n=28). The sensitivity and specificity of the HU value for predicting PE on thoracic CT were as follows: for the right main pulmonary artery, 61.5% and 96.4% at a value of 54.8 (area under the curve [AUC], 0.690); for the left main pulmonary artery, 65.0% and 96.4% at a value of 55.9 (AUC, 0.736); for the right interlobar artery, 44.4% and 96.4% at a value of 62.7 (AUC, 0.615); and for the left interlobar artery, 60.0% and 92.9% at a value of 56.7 (AUC, 0.736). Conclusion HU may exhibit high diagnostic specificity on CT for thrombi up to the interlobar level. An HU value exceeding 54.8 up to the interlobar level may raise suspicion of the presence of PE.
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spelling doaj-art-054a9df7ba744413995e90a5b644dafc2024-11-19T00:09:27ZengThe Korean Society of Emergency MedicineClinical and Experimental Emergency Medicine2383-46252024-09-0111329530310.15441/ceem.23.113527The accuracy of the Hounsfield unit in pulmonary embolism diagnosticsMümin Murat Yazici0Sümeyye Sekmen1Ali Çelik2Özcan Yavaşi3Nur Hürsoy4 Department of Emergency Medicine, Recep Tayyip Erdoğan University Training and Research Hospital, Rize, Turkiye Department of Radiology, Recep Tayyip Erdoğan University Training and Research Hospital, Rize, Turkiye Department of Emergency Medicine, Recep Tayyip Erdoğan University Training and Research Hospital, Rize, Turkiye Department of Emergency Medicine, Recep Tayyip Erdoğan University Training and Research Hospital, Rize, Turkiye Department of Radiology, Recep Tayyip Erdoğan University Training and Research Hospital, Rize, TurkiyeObjective Pulmonary embolism (PE) is a vascular disease that is most frequently diagnosed using the radiological imaging technique computed tomography pulmonary angiography (CTPA). In this study, we aimed to demonstrate the diagnostic accuracy of the Hounsfield unit (HU) for PE based on the hypothesis that acute thrombosis causes an increase in HU value on CT. Methods This research was a single-center, retrospective study. Patients presenting to the emergency department diagnosed with PE on CTPA were enrolled as the study group. Patients admitted to the same emergency department who were not diagnosed with PE and had noncontrast CT scans were included as the control group. A receiver operating curve was produced to determine the diagnostic accuracy of HU values in predicting PE. Results The study population (n=74) consisted of a study group (n=46) and a control group (n=28). The sensitivity and specificity of the HU value for predicting PE on thoracic CT were as follows: for the right main pulmonary artery, 61.5% and 96.4% at a value of 54.8 (area under the curve [AUC], 0.690); for the left main pulmonary artery, 65.0% and 96.4% at a value of 55.9 (AUC, 0.736); for the right interlobar artery, 44.4% and 96.4% at a value of 62.7 (AUC, 0.615); and for the left interlobar artery, 60.0% and 92.9% at a value of 56.7 (AUC, 0.736). Conclusion HU may exhibit high diagnostic specificity on CT for thrombi up to the interlobar level. An HU value exceeding 54.8 up to the interlobar level may raise suspicion of the presence of PE.http://www.ceemjournal.org/upload/pdf/ceem-23-113.pdfhounsfield unit densitypulmonary embolismnoncontrast thorax computed tomography
spellingShingle Mümin Murat Yazici
Sümeyye Sekmen
Ali Çelik
Özcan Yavaşi
Nur Hürsoy
The accuracy of the Hounsfield unit in pulmonary embolism diagnostics
Clinical and Experimental Emergency Medicine
hounsfield unit density
pulmonary embolism
noncontrast thorax computed tomography
title The accuracy of the Hounsfield unit in pulmonary embolism diagnostics
title_full The accuracy of the Hounsfield unit in pulmonary embolism diagnostics
title_fullStr The accuracy of the Hounsfield unit in pulmonary embolism diagnostics
title_full_unstemmed The accuracy of the Hounsfield unit in pulmonary embolism diagnostics
title_short The accuracy of the Hounsfield unit in pulmonary embolism diagnostics
title_sort accuracy of the hounsfield unit in pulmonary embolism diagnostics
topic hounsfield unit density
pulmonary embolism
noncontrast thorax computed tomography
url http://www.ceemjournal.org/upload/pdf/ceem-23-113.pdf
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