DIATOMACEOUS EARTH DURING THE DEPOSITION OF THE IMPURITY PROTEINS IN THE PRODUCTION OF HYBRID PRECURSOR OF INSULIN

The article describes the goal of utilization of diatomiceous earth for the impurities of protein nature sedimentation. The experiments done showed and proved the efficiency of diatomiceous earth as a flocculation agent in the insulin fusion protein production. It was shown that insulin fusion prote...

Full description

Saved in:
Bibliographic Details
Main Authors: A. E. Poludin, D. A. Gusarov, D. A. Burovik
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/459
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The article describes the goal of utilization of diatomiceous earth for the impurities of protein nature sedimentation. The experiments done showed and proved the efficiency of diatomiceous earth as a flocculation agent in the insulin fusion protein production. It was shown that insulin fusion protein being in the solution might be easily separated from admixtures by means of isoelectric point sedimentation with a success help of diatomic earth facilitation the precipitation.
ISSN:2305-2066
2658-5049