Newly identified species from the dog dental plaque microbiome highlight little overlap with humans
Abstract Understudied pet-associated microbiomes represent a rich source for the discovery of microbial taxa important for pet and human health. From a cohort of 23 dogs, we sampled and metagenomically sequenced 64 dental plaque microbiomes, generating 1945 metagenome-assembled genomes spanning 347...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-02-01
|
| Series: | npj Biofilms and Microbiomes |
| Online Access: | https://doi.org/10.1038/s41522-025-00665-2 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849723767750656000 |
|---|---|
| author | Vitor Heidrich Gloria Fackelmann Milka Malesevic Federica Armanini Hrituraj Dey Claudia Mengoni Nemanja Stanisavljevic Goran Vukotic Nicola Segata |
| author_facet | Vitor Heidrich Gloria Fackelmann Milka Malesevic Federica Armanini Hrituraj Dey Claudia Mengoni Nemanja Stanisavljevic Goran Vukotic Nicola Segata |
| author_sort | Vitor Heidrich |
| collection | DOAJ |
| description | Abstract Understudied pet-associated microbiomes represent a rich source for the discovery of microbial taxa important for pet and human health. From a cohort of 23 dogs, we sampled and metagenomically sequenced 64 dental plaque microbiomes, generating 1945 metagenome-assembled genomes spanning 347 microbial species, including 277 undercharacterized species without cultivated representatives. Integration with human microbiome data revealed the dog plaque microbiome is more diverse than – and shows little overlap (5.9% species in common) with – the human plaque microbiome, even though some shared periodontal pathobionts arise as a potential concern. |
| format | Article |
| id | doaj-art-053a3e72f3214f908ef23d40eb0f0b3f |
| institution | DOAJ |
| issn | 2055-5008 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Biofilms and Microbiomes |
| spelling | doaj-art-053a3e72f3214f908ef23d40eb0f0b3f2025-08-20T03:10:55ZengNature Portfolionpj Biofilms and Microbiomes2055-50082025-02-011111610.1038/s41522-025-00665-2Newly identified species from the dog dental plaque microbiome highlight little overlap with humansVitor Heidrich0Gloria Fackelmann1Milka Malesevic2Federica Armanini3Hrituraj Dey4Claudia Mengoni5Nemanja Stanisavljevic6Goran Vukotic7Nicola Segata8Department of Cellular, Computational and Integrative Biology, University of TrentoDepartment of Cellular, Computational and Integrative Biology, University of TrentoInstitute of Molecular Genetics and Genetic Engineering, University of BelgradeDepartment of Cellular, Computational and Integrative Biology, University of TrentoDepartment of Cellular, Computational and Integrative Biology, University of TrentoDepartment of Cellular, Computational and Integrative Biology, University of TrentoInstitute of Molecular Genetics and Genetic Engineering, University of BelgradeInstitute of Molecular Genetics and Genetic Engineering, University of BelgradeDepartment of Cellular, Computational and Integrative Biology, University of TrentoAbstract Understudied pet-associated microbiomes represent a rich source for the discovery of microbial taxa important for pet and human health. From a cohort of 23 dogs, we sampled and metagenomically sequenced 64 dental plaque microbiomes, generating 1945 metagenome-assembled genomes spanning 347 microbial species, including 277 undercharacterized species without cultivated representatives. Integration with human microbiome data revealed the dog plaque microbiome is more diverse than – and shows little overlap (5.9% species in common) with – the human plaque microbiome, even though some shared periodontal pathobionts arise as a potential concern.https://doi.org/10.1038/s41522-025-00665-2 |
| spellingShingle | Vitor Heidrich Gloria Fackelmann Milka Malesevic Federica Armanini Hrituraj Dey Claudia Mengoni Nemanja Stanisavljevic Goran Vukotic Nicola Segata Newly identified species from the dog dental plaque microbiome highlight little overlap with humans npj Biofilms and Microbiomes |
| title | Newly identified species from the dog dental plaque microbiome highlight little overlap with humans |
| title_full | Newly identified species from the dog dental plaque microbiome highlight little overlap with humans |
| title_fullStr | Newly identified species from the dog dental plaque microbiome highlight little overlap with humans |
| title_full_unstemmed | Newly identified species from the dog dental plaque microbiome highlight little overlap with humans |
| title_short | Newly identified species from the dog dental plaque microbiome highlight little overlap with humans |
| title_sort | newly identified species from the dog dental plaque microbiome highlight little overlap with humans |
| url | https://doi.org/10.1038/s41522-025-00665-2 |
| work_keys_str_mv | AT vitorheidrich newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans AT gloriafackelmann newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans AT milkamalesevic newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans AT federicaarmanini newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans AT hriturajdey newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans AT claudiamengoni newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans AT nemanjastanisavljevic newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans AT goranvukotic newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans AT nicolasegata newlyidentifiedspeciesfromthedogdentalplaquemicrobiomehighlightlittleoverlapwithhumans |