A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) readily metastasizes to the lymph nodes, liver, lung, and peritoneum; however, gastric and gallbladder metastases are rare. We report a case of metachronous gastric and gallbladder metastases from PDAC. Case presentation The patient is a 71...

Full description

Saved in:
Bibliographic Details
Main Authors: Makoto Takahashi, Hideyuki Yoshitomi, Atsushi Kato, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Shigetsugu Takano, Kensuke Sugiura, Keishi Kawasaki, Masaru Miyazaki, Masayuki Ohtsuka
Format: Article
Language:English
Published: Japan Surgical Society 2019-02-01
Series:Surgical Case Reports
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40792-019-0581-1
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850094089615179776
author Makoto Takahashi
Hideyuki Yoshitomi
Atsushi Kato
Katsunori Furukawa
Tsukasa Takayashiki
Satoshi Kuboki
Shigetsugu Takano
Kensuke Sugiura
Keishi Kawasaki
Masaru Miyazaki
Masayuki Ohtsuka
author_facet Makoto Takahashi
Hideyuki Yoshitomi
Atsushi Kato
Katsunori Furukawa
Tsukasa Takayashiki
Satoshi Kuboki
Shigetsugu Takano
Kensuke Sugiura
Keishi Kawasaki
Masaru Miyazaki
Masayuki Ohtsuka
author_sort Makoto Takahashi
collection DOAJ
description Abstract Background Pancreatic ductal adenocarcinoma (PDAC) readily metastasizes to the lymph nodes, liver, lung, and peritoneum; however, gastric and gallbladder metastases are rare. We report a case of metachronous gastric and gallbladder metastases from PDAC. Case presentation The patient is a 71-year-old man who underwent distal pancreatectomy for PDAC. Seventeen months after the surgery, a 30-mm nodule was detected at the lesser curvature of the stomach, which was diagnosed as recurrence of PDAC in the lymph nodes. He then received gemcitabine and S-1 combination chemotherapy for 6 months. Because tumor size remained approximately the same and tumor marker levels decreased, total gastrectomy and cholecystectomy were performed. Pathological examination showed well-differentiated tubular adenocarcinoma in the subserosa and muscularis propria of the stomach and gallbladder. The patient remains alive at 41 months after the second surgery with liver metastasis. Conclusion We reported a rare case of metachronous gastric and gallbladder metastases from pancreatic body cancer.
format Article
id doaj-art-0534bd2a6d7349b3bb00159e9fbd35d5
institution DOAJ
issn 2198-7793
language English
publishDate 2019-02-01
publisher Japan Surgical Society
record_format Article
series Surgical Case Reports
spelling doaj-art-0534bd2a6d7349b3bb00159e9fbd35d52025-08-20T02:41:45ZengJapan Surgical SocietySurgical Case Reports2198-77932019-02-01511410.1186/s40792-019-0581-1A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancerMakoto Takahashi0Hideyuki Yoshitomi1Atsushi Kato2Katsunori Furukawa3Tsukasa Takayashiki4Satoshi Kuboki5Shigetsugu Takano6Kensuke Sugiura7Keishi Kawasaki8Masaru Miyazaki9Masayuki Ohtsuka10Department of General Surgery, Chiba University, Graduate School of MedicineDepartment of General Surgery, Chiba University, Graduate School of MedicineDigestive Diseases Center, International University of Health and Welfare, Mita HospitalDepartment of General Surgery, Chiba University, Graduate School of MedicineDepartment of General Surgery, Chiba University, Graduate School of MedicineDepartment of General Surgery, Chiba University, Graduate School of MedicineDepartment of General Surgery, Chiba University, Graduate School of MedicineDepartment of General Surgery, Chiba University, Graduate School of MedicineDepartment of General Surgery, Chiba University, Graduate School of MedicineDepartment of General Surgery, Chiba University, Graduate School of MedicineDepartment of General Surgery, Chiba University, Graduate School of MedicineAbstract Background Pancreatic ductal adenocarcinoma (PDAC) readily metastasizes to the lymph nodes, liver, lung, and peritoneum; however, gastric and gallbladder metastases are rare. We report a case of metachronous gastric and gallbladder metastases from PDAC. Case presentation The patient is a 71-year-old man who underwent distal pancreatectomy for PDAC. Seventeen months after the surgery, a 30-mm nodule was detected at the lesser curvature of the stomach, which was diagnosed as recurrence of PDAC in the lymph nodes. He then received gemcitabine and S-1 combination chemotherapy for 6 months. Because tumor size remained approximately the same and tumor marker levels decreased, total gastrectomy and cholecystectomy were performed. Pathological examination showed well-differentiated tubular adenocarcinoma in the subserosa and muscularis propria of the stomach and gallbladder. The patient remains alive at 41 months after the second surgery with liver metastasis. Conclusion We reported a rare case of metachronous gastric and gallbladder metastases from pancreatic body cancer.http://link.springer.com/article/10.1186/s40792-019-0581-1Pancreatic cancerMetachronous gastric metastasisMetachronous gallbladder metastasisSurgery
spellingShingle Makoto Takahashi
Hideyuki Yoshitomi
Atsushi Kato
Katsunori Furukawa
Tsukasa Takayashiki
Satoshi Kuboki
Shigetsugu Takano
Kensuke Sugiura
Keishi Kawasaki
Masaru Miyazaki
Masayuki Ohtsuka
A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer
Surgical Case Reports
Pancreatic cancer
Metachronous gastric metastasis
Metachronous gallbladder metastasis
Surgery
title A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer
title_full A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer
title_fullStr A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer
title_full_unstemmed A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer
title_short A case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer
title_sort case of successfully resected metachronous gastric and gallbladder metastases from pancreatic body cancer
topic Pancreatic cancer
Metachronous gastric metastasis
Metachronous gallbladder metastasis
Surgery
url http://link.springer.com/article/10.1186/s40792-019-0581-1
work_keys_str_mv AT makototakahashi acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT hideyukiyoshitomi acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT atsushikato acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT katsunorifurukawa acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT tsukasatakayashiki acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT satoshikuboki acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT shigetsugutakano acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT kensukesugiura acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT keishikawasaki acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT masarumiyazaki acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT masayukiohtsuka acaseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT makototakahashi caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT hideyukiyoshitomi caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT atsushikato caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT katsunorifurukawa caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT tsukasatakayashiki caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT satoshikuboki caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT shigetsugutakano caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT kensukesugiura caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT keishikawasaki caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT masarumiyazaki caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer
AT masayukiohtsuka caseofsuccessfullyresectedmetachronousgastricandgallbladdermetastasesfrompancreaticbodycancer