Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of Literature
Postallogenic hematopoietic stem cell transplant (post-allo-HSCT) erythrocytosis is a rare phenomenon mostly seen in cases of aplastic anemia. It is a well-known complication in renal transplant recipients. Clinical evaluation, serum erythropoietin (EPO) level, and Janus kinase 2 (JAK 2) mutation ar...
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| author | Sherry S. Abraham Saikumar Soman Akshaya B. Ajish Sreejith G. Nair |
| author_facet | Sherry S. Abraham Saikumar Soman Akshaya B. Ajish Sreejith G. Nair |
| author_sort | Sherry S. Abraham |
| collection | DOAJ |
| description | Postallogenic hematopoietic stem cell transplant (post-allo-HSCT) erythrocytosis is a rare phenomenon mostly seen in cases of aplastic anemia. It is a well-known complication in renal transplant recipients. Clinical evaluation, serum erythropoietin (EPO) level, and Janus kinase 2 (JAK 2) mutation are important to differentiate between primary and secondary erythrocytoses. Treatment aims at normalizing the clinical, physical, and laboratory parameters and minimizing thromboembolic complications. The majority of the patients have a favorable outcome with phlebotomies and low-dose aspirin. We report a rare case of post-allo-HSCT erythrocytosis in a patient who underwent related allo-HSCT for acute myeloid leukemia. |
| format | Article |
| id | doaj-art-05331b41b41c42588d7dd8fb66b59b56 |
| institution | Kabale University |
| issn | 0971-5851 0975-2129 |
| language | English |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-05331b41b41c42588d7dd8fb66b59b562025-08-20T03:44:50ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-212910.1055/s-0044-1791532Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of LiteratureSherry S. Abraham0https://orcid.org/0009-0000-4765-6179Saikumar Soman1Akshaya B. Ajish2Sreejith G. Nair3Department of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, IndiaDepartment of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, IndiaDepartment of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, IndiaDepartment of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, IndiaPostallogenic hematopoietic stem cell transplant (post-allo-HSCT) erythrocytosis is a rare phenomenon mostly seen in cases of aplastic anemia. It is a well-known complication in renal transplant recipients. Clinical evaluation, serum erythropoietin (EPO) level, and Janus kinase 2 (JAK 2) mutation are important to differentiate between primary and secondary erythrocytoses. Treatment aims at normalizing the clinical, physical, and laboratory parameters and minimizing thromboembolic complications. The majority of the patients have a favorable outcome with phlebotomies and low-dose aspirin. We report a rare case of post-allo-HSCT erythrocytosis in a patient who underwent related allo-HSCT for acute myeloid leukemia.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1791532erythrocytosisallogenic hematopoietic stem cell transplantacute myeloid leukemia |
| spellingShingle | Sherry S. Abraham Saikumar Soman Akshaya B. Ajish Sreejith G. Nair Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of Literature Indian Journal of Medical and Paediatric Oncology erythrocytosis allogenic hematopoietic stem cell transplant acute myeloid leukemia |
| title | Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of Literature |
| title_full | Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of Literature |
| title_fullStr | Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of Literature |
| title_full_unstemmed | Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of Literature |
| title_short | Posttransplant Erythrocytosis after Allogenic Stem Cell Transplant for Acute Myeloid Leukemia: A Case Report and Review of Literature |
| title_sort | posttransplant erythrocytosis after allogenic stem cell transplant for acute myeloid leukemia a case report and review of literature |
| topic | erythrocytosis allogenic hematopoietic stem cell transplant acute myeloid leukemia |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1791532 |
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