Endovascular Intervention for Acute Ischemic Stroke in Light of Recent Trials

Three recently published trials, MR RESCUE, IMS III, and SYNTHESIS Expansion, evaluating the efficacy and safety of endovascular treatment of acute ischemic stroke have generated concerns about the future of endovascular approach. However, the tremendous evolution that imaging and endovascular treat...

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Main Authors: Kenan Alkhalili, Nohra Chalouhi, Stavropoula Tjoumakaris, David Hasan, Robert M. Starke, Mario Zanaty, Robert H. Rosenwasser, Pascal Jabbour
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/429549
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author Kenan Alkhalili
Nohra Chalouhi
Stavropoula Tjoumakaris
David Hasan
Robert M. Starke
Mario Zanaty
Robert H. Rosenwasser
Pascal Jabbour
author_facet Kenan Alkhalili
Nohra Chalouhi
Stavropoula Tjoumakaris
David Hasan
Robert M. Starke
Mario Zanaty
Robert H. Rosenwasser
Pascal Jabbour
author_sort Kenan Alkhalili
collection DOAJ
description Three recently published trials, MR RESCUE, IMS III, and SYNTHESIS Expansion, evaluating the efficacy and safety of endovascular treatment of acute ischemic stroke have generated concerns about the future of endovascular approach. However, the tremendous evolution that imaging and endovascular treatment modalities have undergone over the past several years has raised doubts about the validity of these trials. In this paper, we review the role of endovascular treatment strategies in acute ischemic stroke and discuss the limitations and shortcomings that prevent generalization of the findings of recent trials. We also provide our experience in endovascular treatment of acute ischemic stroke.
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institution Kabale University
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publishDate 2014-01-01
publisher Wiley
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spelling doaj-art-05285990b9824cb98159b07abd9602102025-02-03T05:57:33ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/429549429549Endovascular Intervention for Acute Ischemic Stroke in Light of Recent TrialsKenan Alkhalili0Nohra Chalouhi1Stavropoula Tjoumakaris2David Hasan3Robert M. Starke4Mario Zanaty5Robert H. Rosenwasser6Pascal Jabbour7Department of Surgery, University of Arizona, Tucson, AZ 85721, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, University of Iowa, Iowa City, IA 52242, USADepartment of Neurosurgery, University of Virginia, Charlottesville, VA 22908, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USAThree recently published trials, MR RESCUE, IMS III, and SYNTHESIS Expansion, evaluating the efficacy and safety of endovascular treatment of acute ischemic stroke have generated concerns about the future of endovascular approach. However, the tremendous evolution that imaging and endovascular treatment modalities have undergone over the past several years has raised doubts about the validity of these trials. In this paper, we review the role of endovascular treatment strategies in acute ischemic stroke and discuss the limitations and shortcomings that prevent generalization of the findings of recent trials. We also provide our experience in endovascular treatment of acute ischemic stroke.http://dx.doi.org/10.1155/2014/429549
spellingShingle Kenan Alkhalili
Nohra Chalouhi
Stavropoula Tjoumakaris
David Hasan
Robert M. Starke
Mario Zanaty
Robert H. Rosenwasser
Pascal Jabbour
Endovascular Intervention for Acute Ischemic Stroke in Light of Recent Trials
The Scientific World Journal
title Endovascular Intervention for Acute Ischemic Stroke in Light of Recent Trials
title_full Endovascular Intervention for Acute Ischemic Stroke in Light of Recent Trials
title_fullStr Endovascular Intervention for Acute Ischemic Stroke in Light of Recent Trials
title_full_unstemmed Endovascular Intervention for Acute Ischemic Stroke in Light of Recent Trials
title_short Endovascular Intervention for Acute Ischemic Stroke in Light of Recent Trials
title_sort endovascular intervention for acute ischemic stroke in light of recent trials
url http://dx.doi.org/10.1155/2014/429549
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AT robertmstarke endovascularinterventionforacuteischemicstrokeinlightofrecenttrials
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