Physiological, biochemical and histological effects of abscisic acid-synthesized silver and copper oxide nanoparticles on the potato tuber moth, Phthorimaea operculella

Abstract Background The potato tuber moth (PTM), Phthorimaea operculella, poses a significant threat to potato cultivation in tropical and subtropical regions. Chemical control, though widely used, poses risks to human and environmental health, necessitating safer alternatives. This study investigat...

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Main Authors: Amr S. Abou El-Ela, Chao Zhang, Asim Munawar, Xuan Chen, Yixin Zhang, Eric Siaw Ntiri, Modhi O. Alotaibi, Amr Elkelish, Suhailah S. Aljameel, Wenwu Zhou, Zeng-Rong Zhu
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Chemical and Biological Technologies in Agriculture
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Online Access:https://doi.org/10.1186/s40538-025-00782-2
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author Amr S. Abou El-Ela
Chao Zhang
Asim Munawar
Xuan Chen
Yixin Zhang
Eric Siaw Ntiri
Modhi O. Alotaibi
Amr Elkelish
Suhailah S. Aljameel
Wenwu Zhou
Zeng-Rong Zhu
author_facet Amr S. Abou El-Ela
Chao Zhang
Asim Munawar
Xuan Chen
Yixin Zhang
Eric Siaw Ntiri
Modhi O. Alotaibi
Amr Elkelish
Suhailah S. Aljameel
Wenwu Zhou
Zeng-Rong Zhu
author_sort Amr S. Abou El-Ela
collection DOAJ
description Abstract Background The potato tuber moth (PTM), Phthorimaea operculella, poses a significant threat to potato cultivation in tropical and subtropical regions. Chemical control, though widely used, poses risks to human and environmental health, necessitating safer alternatives. This study investigated eco-friendly alternatives by synthesizing silver (AgNPs) and copper oxide nanoparticles (CuONPs) using abscisic acid (ABA). Results Characterization through UV–vis spectroscopy, scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray, X-ray diffraction, Fourier transform infrared spectroscopy, and zeta potential analysis confirmed the successful synthesis of AgNPs with a uniform size of 35.8 nm and a plasmon resonance at 430 nm. CuONPs displayed a porous, rugby sheet-like structure, with a thickness of 68.5 nm and a 290 nm absorption peak. The effectiveness of the nanoparticles against PTM larvae was assessed through larval spraying and leaf-dipping. Larval spraying outperformed leaf-dipping, with median lethal concentration (LC50) values of 670 mg/L for AgNPs and 1320 mg/L for CuONPs. AgNPs and CuONPs significantly altered digestive enzyme activities in treated PTM larvae, reducing α-amylase, β-glucosidase, lipase, protease, and trypsin, and increasing acid phosphatase activity. Histological studies revealed damage to the larvae's midgut epithelial layer and peritrophic membrane, resulting in nuclei dispersion. Conclusions Our study shows a cost-effective, minimal-impact strategy for synthesizing AgNPs and CuONPs, which can serve as a potential approach for managing PTM. Graphical abstract
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spelling doaj-art-05201002e1d74baaa5eb91702aa84f5d2025-08-20T03:04:26ZengSpringerOpenChemical and Biological Technologies in Agriculture2196-56412025-05-0112112010.1186/s40538-025-00782-2Physiological, biochemical and histological effects of abscisic acid-synthesized silver and copper oxide nanoparticles on the potato tuber moth, Phthorimaea operculellaAmr S. Abou El-Ela0Chao Zhang1Asim Munawar2Xuan Chen3Yixin Zhang4Eric Siaw Ntiri5Modhi O. Alotaibi6Amr Elkelish7Suhailah S. Aljameel8Wenwu Zhou9Zeng-Rong Zhu10State Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang UniversityState Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang UniversityState Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang UniversityState Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang UniversityState Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang UniversityState Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang UniversityDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman UniversityBiology Department, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU)Department of Chemistry, College of Science, Imam Abdulrahman Bin Faisal UniversityState Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang UniversityState Key Laboratory of Rice Biology and Breeding, Ministry of Agricultural and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Insect Sciences, Zhejiang UniversityAbstract Background The potato tuber moth (PTM), Phthorimaea operculella, poses a significant threat to potato cultivation in tropical and subtropical regions. Chemical control, though widely used, poses risks to human and environmental health, necessitating safer alternatives. This study investigated eco-friendly alternatives by synthesizing silver (AgNPs) and copper oxide nanoparticles (CuONPs) using abscisic acid (ABA). Results Characterization through UV–vis spectroscopy, scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray, X-ray diffraction, Fourier transform infrared spectroscopy, and zeta potential analysis confirmed the successful synthesis of AgNPs with a uniform size of 35.8 nm and a plasmon resonance at 430 nm. CuONPs displayed a porous, rugby sheet-like structure, with a thickness of 68.5 nm and a 290 nm absorption peak. The effectiveness of the nanoparticles against PTM larvae was assessed through larval spraying and leaf-dipping. Larval spraying outperformed leaf-dipping, with median lethal concentration (LC50) values of 670 mg/L for AgNPs and 1320 mg/L for CuONPs. AgNPs and CuONPs significantly altered digestive enzyme activities in treated PTM larvae, reducing α-amylase, β-glucosidase, lipase, protease, and trypsin, and increasing acid phosphatase activity. Histological studies revealed damage to the larvae's midgut epithelial layer and peritrophic membrane, resulting in nuclei dispersion. Conclusions Our study shows a cost-effective, minimal-impact strategy for synthesizing AgNPs and CuONPs, which can serve as a potential approach for managing PTM. Graphical abstracthttps://doi.org/10.1186/s40538-025-00782-2Abscisic acidSilver nanoparticlesCopper oxide nanoparticlesPhthorimaea operculellaDigestive enzymes
spellingShingle Amr S. Abou El-Ela
Chao Zhang
Asim Munawar
Xuan Chen
Yixin Zhang
Eric Siaw Ntiri
Modhi O. Alotaibi
Amr Elkelish
Suhailah S. Aljameel
Wenwu Zhou
Zeng-Rong Zhu
Physiological, biochemical and histological effects of abscisic acid-synthesized silver and copper oxide nanoparticles on the potato tuber moth, Phthorimaea operculella
Chemical and Biological Technologies in Agriculture
Abscisic acid
Silver nanoparticles
Copper oxide nanoparticles
Phthorimaea operculella
Digestive enzymes
title Physiological, biochemical and histological effects of abscisic acid-synthesized silver and copper oxide nanoparticles on the potato tuber moth, Phthorimaea operculella
title_full Physiological, biochemical and histological effects of abscisic acid-synthesized silver and copper oxide nanoparticles on the potato tuber moth, Phthorimaea operculella
title_fullStr Physiological, biochemical and histological effects of abscisic acid-synthesized silver and copper oxide nanoparticles on the potato tuber moth, Phthorimaea operculella
title_full_unstemmed Physiological, biochemical and histological effects of abscisic acid-synthesized silver and copper oxide nanoparticles on the potato tuber moth, Phthorimaea operculella
title_short Physiological, biochemical and histological effects of abscisic acid-synthesized silver and copper oxide nanoparticles on the potato tuber moth, Phthorimaea operculella
title_sort physiological biochemical and histological effects of abscisic acid synthesized silver and copper oxide nanoparticles on the potato tuber moth phthorimaea operculella
topic Abscisic acid
Silver nanoparticles
Copper oxide nanoparticles
Phthorimaea operculella
Digestive enzymes
url https://doi.org/10.1186/s40538-025-00782-2
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