The pseudoknot region and poly-(C) tract comprise an essential RNA packaging signal for assembly of foot-and-mouth disease virus.
Virus assembly is a crucial step for the completion of the viral replication cycle. In addition to ensuring efficient incorporation of viral genomes into nascent virions, high specificity is required to prevent incorporation of host nucleic acids. For picornaviruses, including FMDV, the mechanisms r...
Saved in:
| Main Authors: | Chris Neil, Joseph Newman, Nicola J Stonehouse, David J Rowlands, Graham J Belsham, Tobias J Tuthill |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-12-01
|
| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1012283 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication, but essential for the production of infectious virus.
by: Joseph C Ward, et al.
Published: (2022-06-01) -
Foot-and-Mouth Disease Vaccines by Design; Production of Capsid-Modified Foot-and-Mouth Disease Viruses with Improved Cell Culture Growth
by: Stephen Berryman, et al.
Published: (2025-03-01) -
Reconstruction of the transmission history of RNA virus outbreaks using full genome sequences: foot-and-mouth disease virus in Bulgaria in 2011.
by: Begoña Valdazo-González, et al.
Published: (2012-01-01) -
Transmission pathways of foot-and-mouth disease virus in the United Kingdom in 2007.
by: Eleanor M Cottam, et al.
Published: (2008-04-01) -
Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts.
by: Rebecca Chandler-Bostock, et al.
Published: (2020-12-01)