Research trends of piezoelectric materials in neurodegenerative disease applications
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and huntington's disease, pose significant threats to human health, with current treatment options remaining limited. Piezoelectric materials, known for their a...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2025-10-01
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| Series: | Bioactive Materials |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X25002506 |
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| author | Xueqian Wang Yuhao Sun Chengyao Han Xinxian Meng Ke Wen Jingshu Wu Peiru Min Ke Li Yixin Zhang |
| author_facet | Xueqian Wang Yuhao Sun Chengyao Han Xinxian Meng Ke Wen Jingshu Wu Peiru Min Ke Li Yixin Zhang |
| author_sort | Xueqian Wang |
| collection | DOAJ |
| description | Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and huntington's disease, pose significant threats to human health, with current treatment options remaining limited. Piezoelectric materials, known for their ability to convert mechanical energy into electrical signals at the nanoscale, hold great promise in the diagnosis and treatment of neurodegenerative diseases due to their excellent electromechanical properties, environmental stability, and sensitivity. This review systematically outlines the working principles and classifications of piezoelectric materials. Subsequently, the recent advances in piezoelectric materials and their applications in the diagnosis and treatment of neurodegenerative diseases are highlighted. Finally, the challenges and perspectives regarding the development of future piezoelectric materials are discussed. This review aims to provide a comprehensive reference for the further application of piezoelectric materials in neurodegenerative diseases. |
| format | Article |
| id | doaj-art-050f78518e944bcaabe2cdd7add3fffe |
| institution | Kabale University |
| issn | 2452-199X |
| language | English |
| publishDate | 2025-10-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj-art-050f78518e944bcaabe2cdd7add3fffe2025-08-24T05:13:46ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2025-10-015236639210.1016/j.bioactmat.2025.06.022Research trends of piezoelectric materials in neurodegenerative disease applicationsXueqian Wang0Yuhao Sun1Chengyao Han2Xinxian Meng3Ke Wen4Jingshu Wu5Peiru Min6Ke Li7Yixin Zhang8Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaCorresponding author.; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaCorresponding author.; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, ChinaNeurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and huntington's disease, pose significant threats to human health, with current treatment options remaining limited. Piezoelectric materials, known for their ability to convert mechanical energy into electrical signals at the nanoscale, hold great promise in the diagnosis and treatment of neurodegenerative diseases due to their excellent electromechanical properties, environmental stability, and sensitivity. This review systematically outlines the working principles and classifications of piezoelectric materials. Subsequently, the recent advances in piezoelectric materials and their applications in the diagnosis and treatment of neurodegenerative diseases are highlighted. Finally, the challenges and perspectives regarding the development of future piezoelectric materials are discussed. This review aims to provide a comprehensive reference for the further application of piezoelectric materials in neurodegenerative diseases.http://www.sciencedirect.com/science/article/pii/S2452199X25002506Piezoelectric materialsPiezoelectricityNeurodegenerative diseasesDiagnosisTreatment |
| spellingShingle | Xueqian Wang Yuhao Sun Chengyao Han Xinxian Meng Ke Wen Jingshu Wu Peiru Min Ke Li Yixin Zhang Research trends of piezoelectric materials in neurodegenerative disease applications Bioactive Materials Piezoelectric materials Piezoelectricity Neurodegenerative diseases Diagnosis Treatment |
| title | Research trends of piezoelectric materials in neurodegenerative disease applications |
| title_full | Research trends of piezoelectric materials in neurodegenerative disease applications |
| title_fullStr | Research trends of piezoelectric materials in neurodegenerative disease applications |
| title_full_unstemmed | Research trends of piezoelectric materials in neurodegenerative disease applications |
| title_short | Research trends of piezoelectric materials in neurodegenerative disease applications |
| title_sort | research trends of piezoelectric materials in neurodegenerative disease applications |
| topic | Piezoelectric materials Piezoelectricity Neurodegenerative diseases Diagnosis Treatment |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X25002506 |
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