Myocardial perfusion scintigraphy in identification and localization of individual coronary lesions
The aim of this study was to evaluate the accuracy of myocardial perfusion scintigraphy with technetium-99m tetrofosmin by single-photon emission computed tomography (SPECT), using one-day protocol in the identification and localization of individual stenosed coronary vessels. Sixty-eight patients w...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2004-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500404371B.pdf |
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| author | Baškot Branislav Janković Zoran Marković Milić Spaić Rajko |
| author_facet | Baškot Branislav Janković Zoran Marković Milić Spaić Rajko |
| author_sort | Baškot Branislav |
| collection | DOAJ |
| description | The aim of this study was to evaluate the accuracy of myocardial perfusion scintigraphy with technetium-99m tetrofosmin by single-photon emission computed tomography (SPECT), using one-day protocol in the identification and localization of individual stenosed coronary vessels. Sixty-eight patients with suspected coronary artery disease (CAD) were studied. In thirty of them coronary angiography showed significant stenosis (³50%). Nine patients were with one-vessel disease, 11 were with two-vessel disease, and 10 were with three-vessel disease. All the patients were administered two i.v. injections of 99mTc tetrofosmin, one at peak pharmacologic exercise (1-3 min after i.v. administration of dipiridamol 0.56 mg per kg during 4 min) 370 MBq, and the other 740 MBq at rest 3 hrs after the exercise test (acquisition was obtained 15-30 min after injections for both studies). Overall sensitivity, specificity, and diagnostic accuracy in the identification of individual stenosed coronary vessels were 90%, 86%, and 88%, respectively. Sensitivity, specificity, and accuracy in each of the individual vascular territories were not significantly different: LAD (96% 64%, and 75%), ACx (73%, 100%, and 94%), RCA (95%, 93%, and 94%). The results of this study demonstrated one-day 99mTc-tetrofosmin SPECT scintigraphy to be suitable and accurate technique for the identification and localization of individual stenosed coronary vessels, as well as a highly sensitive method in the recognition of one- and multiple-vessel diseases of coronary arteries. |
| format | Article |
| id | doaj-art-0509cf9e850a41e4a0ec394bf3e2f6a0 |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2004-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-0509cf9e850a41e4a0ec394bf3e2f6a02025-08-20T03:16:35ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502004-01-0161437137710.2298/VSP0404371BMyocardial perfusion scintigraphy in identification and localization of individual coronary lesionsBaškot BranislavJanković ZoranMarković MilićSpaić RajkoThe aim of this study was to evaluate the accuracy of myocardial perfusion scintigraphy with technetium-99m tetrofosmin by single-photon emission computed tomography (SPECT), using one-day protocol in the identification and localization of individual stenosed coronary vessels. Sixty-eight patients with suspected coronary artery disease (CAD) were studied. In thirty of them coronary angiography showed significant stenosis (³50%). Nine patients were with one-vessel disease, 11 were with two-vessel disease, and 10 were with three-vessel disease. All the patients were administered two i.v. injections of 99mTc tetrofosmin, one at peak pharmacologic exercise (1-3 min after i.v. administration of dipiridamol 0.56 mg per kg during 4 min) 370 MBq, and the other 740 MBq at rest 3 hrs after the exercise test (acquisition was obtained 15-30 min after injections for both studies). Overall sensitivity, specificity, and diagnostic accuracy in the identification of individual stenosed coronary vessels were 90%, 86%, and 88%, respectively. Sensitivity, specificity, and accuracy in each of the individual vascular territories were not significantly different: LAD (96% 64%, and 75%), ACx (73%, 100%, and 94%), RCA (95%, 93%, and 94%). The results of this study demonstrated one-day 99mTc-tetrofosmin SPECT scintigraphy to be suitable and accurate technique for the identification and localization of individual stenosed coronary vessels, as well as a highly sensitive method in the recognition of one- and multiple-vessel diseases of coronary arteries.http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500404371B.pdfmyocardial ischemiacoronary diseasetomographyemission-computedsingle-photontechnetium |
| spellingShingle | Baškot Branislav Janković Zoran Marković Milić Spaić Rajko Myocardial perfusion scintigraphy in identification and localization of individual coronary lesions Vojnosanitetski Pregled myocardial ischemia coronary disease tomography emission-computed single-photon technetium |
| title | Myocardial perfusion scintigraphy in identification and localization of individual coronary lesions |
| title_full | Myocardial perfusion scintigraphy in identification and localization of individual coronary lesions |
| title_fullStr | Myocardial perfusion scintigraphy in identification and localization of individual coronary lesions |
| title_full_unstemmed | Myocardial perfusion scintigraphy in identification and localization of individual coronary lesions |
| title_short | Myocardial perfusion scintigraphy in identification and localization of individual coronary lesions |
| title_sort | myocardial perfusion scintigraphy in identification and localization of individual coronary lesions |
| topic | myocardial ischemia coronary disease tomography emission-computed single-photon technetium |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2004/0042-84500404371B.pdf |
| work_keys_str_mv | AT baskotbranislav myocardialperfusionscintigraphyinidentificationandlocalizationofindividualcoronarylesions AT jankoviczoran myocardialperfusionscintigraphyinidentificationandlocalizationofindividualcoronarylesions AT markovicmilic myocardialperfusionscintigraphyinidentificationandlocalizationofindividualcoronarylesions AT spaicrajko myocardialperfusionscintigraphyinidentificationandlocalizationofindividualcoronarylesions |