Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract Surgery
Dexmedetomidine is an elective alpha-2 adrenergic agonist, being used in anesthesia practice. It offers sedative, anxiolytic, analgesic, muscle relaxant, and sympathetic lytic properties. While respiratory effects are considered minor, there are important cardiovascular side effects with bradycardia...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Anesthesiology |
| Online Access: | http://dx.doi.org/10.1155/2018/2896032 |
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| author | Amaniti Aikaterini Dalakakis Ioannis Gkinas Dimitrios Sapalidis Konstantinos Grosomanidis Vasilios Papazisis George |
| author_facet | Amaniti Aikaterini Dalakakis Ioannis Gkinas Dimitrios Sapalidis Konstantinos Grosomanidis Vasilios Papazisis George |
| author_sort | Amaniti Aikaterini |
| collection | DOAJ |
| description | Dexmedetomidine is an elective alpha-2 adrenergic agonist, being used in anesthesia practice. It offers sedative, anxiolytic, analgesic, muscle relaxant, and sympathetic lytic properties. While respiratory effects are considered minor, there are important cardiovascular side effects with bradycardia and hypotension being the most common. This article presents a case of a patient, with significant comorbidities and polypharmacy, who was scheduled for cataract surgery under dexmedetomidine sedation. During the administration, severe hemodynamic deterioration was observed with bradycardia and hypotension leading to asystole. Cardiac arrest was successfully managed in accordance with the guidelines of the European Resuscitation Council. Despite the promising role of dexmedetomidine in anesthesia practice, the associated adverse effects cannot be ignored. For this reason it is obligatory to have the minimum mandatory monitoring in accordance with the safety and quality guidelines. |
| format | Article |
| id | doaj-art-04ff506974c6468eb0e00a2eefd345e6 |
| institution | OA Journals |
| issn | 2090-6382 2090-6390 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Anesthesiology |
| spelling | doaj-art-04ff506974c6468eb0e00a2eefd345e62025-08-20T02:03:00ZengWileyCase Reports in Anesthesiology2090-63822090-63902018-01-01201810.1155/2018/28960322896032Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract SurgeryAmaniti Aikaterini0Dalakakis Ioannis1Gkinas Dimitrios2Sapalidis Konstantinos3Grosomanidis Vasilios4Papazisis George5AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, GreeceAHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, GreeceAHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, GreeceAHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, GreeceAHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, GreeceLaboratory of Pharmacology, Aristotle University of Thessaloniki, Thessaloniki, GreeceDexmedetomidine is an elective alpha-2 adrenergic agonist, being used in anesthesia practice. It offers sedative, anxiolytic, analgesic, muscle relaxant, and sympathetic lytic properties. While respiratory effects are considered minor, there are important cardiovascular side effects with bradycardia and hypotension being the most common. This article presents a case of a patient, with significant comorbidities and polypharmacy, who was scheduled for cataract surgery under dexmedetomidine sedation. During the administration, severe hemodynamic deterioration was observed with bradycardia and hypotension leading to asystole. Cardiac arrest was successfully managed in accordance with the guidelines of the European Resuscitation Council. Despite the promising role of dexmedetomidine in anesthesia practice, the associated adverse effects cannot be ignored. For this reason it is obligatory to have the minimum mandatory monitoring in accordance with the safety and quality guidelines.http://dx.doi.org/10.1155/2018/2896032 |
| spellingShingle | Amaniti Aikaterini Dalakakis Ioannis Gkinas Dimitrios Sapalidis Konstantinos Grosomanidis Vasilios Papazisis George Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract Surgery Case Reports in Anesthesiology |
| title | Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract Surgery |
| title_full | Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract Surgery |
| title_fullStr | Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract Surgery |
| title_full_unstemmed | Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract Surgery |
| title_short | Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract Surgery |
| title_sort | bradycardia leading to asystole following dexmedetomidine infusion during cataract surgery dexmedetomidine induced asystole for cataract surgery |
| url | http://dx.doi.org/10.1155/2018/2896032 |
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