Peripheral Blood Leukocytes and Serum Nested Polymerase Chain Reaction Are Complementary Methods for Monitoring Active Cytomegalovirus Infection in Transplant Patients

BACKGROUND: Human cytomegalovirus is an important cause of morbidity and mortality in immunocompromised patients. Qualitative polymerase chain reaction (PCR) has proven to be a sensitive and effective technique in defining active cytomegalovirus infection, in addition to having low cost and being a...

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Main Authors: PD Andrade, MT Fioravanti, EBV Anjos, C De Oliveira, DM Albuquerque, SCB Costa
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2013/214631
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author PD Andrade
MT Fioravanti
EBV Anjos
C De Oliveira
DM Albuquerque
SCB Costa
author_facet PD Andrade
MT Fioravanti
EBV Anjos
C De Oliveira
DM Albuquerque
SCB Costa
author_sort PD Andrade
collection DOAJ
description BACKGROUND: Human cytomegalovirus is an important cause of morbidity and mortality in immunocompromised patients. Qualitative polymerase chain reaction (PCR) has proven to be a sensitive and effective technique in defining active cytomegalovirus infection, in addition to having low cost and being a useful test for situations in which there is no need for quantification. Real-time PCR has the advantage of quantification; however, the high cost of this methodology makes it impractical for routine use.
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institution Kabale University
issn 1712-9532
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-04fa4b6b81bc49a49314f72d9e59bf6f2025-08-20T03:54:25ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322013-01-01243e69e7410.1155/2013/214631Peripheral Blood Leukocytes and Serum Nested Polymerase Chain Reaction Are Complementary Methods for Monitoring Active Cytomegalovirus Infection in Transplant PatientsPD Andrade0MT Fioravanti1EBV Anjos2C De Oliveira3DM Albuquerque4SCB Costa5Department of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, São Paulo, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, São Paulo, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, São Paulo, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, São Paulo, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, São Paulo, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (Unicamp), Campinas, São Paulo, BrazilBACKGROUND: Human cytomegalovirus is an important cause of morbidity and mortality in immunocompromised patients. Qualitative polymerase chain reaction (PCR) has proven to be a sensitive and effective technique in defining active cytomegalovirus infection, in addition to having low cost and being a useful test for situations in which there is no need for quantification. Real-time PCR has the advantage of quantification; however, the high cost of this methodology makes it impractical for routine use.http://dx.doi.org/10.1155/2013/214631
spellingShingle PD Andrade
MT Fioravanti
EBV Anjos
C De Oliveira
DM Albuquerque
SCB Costa
Peripheral Blood Leukocytes and Serum Nested Polymerase Chain Reaction Are Complementary Methods for Monitoring Active Cytomegalovirus Infection in Transplant Patients
Canadian Journal of Infectious Diseases and Medical Microbiology
title Peripheral Blood Leukocytes and Serum Nested Polymerase Chain Reaction Are Complementary Methods for Monitoring Active Cytomegalovirus Infection in Transplant Patients
title_full Peripheral Blood Leukocytes and Serum Nested Polymerase Chain Reaction Are Complementary Methods for Monitoring Active Cytomegalovirus Infection in Transplant Patients
title_fullStr Peripheral Blood Leukocytes and Serum Nested Polymerase Chain Reaction Are Complementary Methods for Monitoring Active Cytomegalovirus Infection in Transplant Patients
title_full_unstemmed Peripheral Blood Leukocytes and Serum Nested Polymerase Chain Reaction Are Complementary Methods for Monitoring Active Cytomegalovirus Infection in Transplant Patients
title_short Peripheral Blood Leukocytes and Serum Nested Polymerase Chain Reaction Are Complementary Methods for Monitoring Active Cytomegalovirus Infection in Transplant Patients
title_sort peripheral blood leukocytes and serum nested polymerase chain reaction are complementary methods for monitoring active cytomegalovirus infection in transplant patients
url http://dx.doi.org/10.1155/2013/214631
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