Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity
Although colonoscopy remains the gold standard for Ulcerative colitis (UC) diagnosis due to its invasive and costly nature, non-invasive biomarkers are gaining importance in disease activity monitoring and diagnosis. In our study, we aimed to evaluate the correlation of fecal calprotectin (FC) and f...
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| Format: | Article |
| Language: | English |
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Sciendo
2025-01-01
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| Series: | Romanian Journal of Laboratory Medicine |
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| Online Access: | https://doi.org/10.2478/rrlm-2025-0001 |
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| _version_ | 1823860396677660672 |
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| author | Büşra Usta Demet Gür Vural Asuman Birinci Müge Ustaoğlu Dede |
| author_facet | Büşra Usta Demet Gür Vural Asuman Birinci Müge Ustaoğlu Dede |
| author_sort | Büşra Usta |
| collection | DOAJ |
| description | Although colonoscopy remains the gold standard for Ulcerative colitis (UC) diagnosis due to its invasive and costly nature, non-invasive biomarkers are gaining importance in disease activity monitoring and diagnosis. In our study, we aimed to evaluate the correlation of fecal calprotectin (FC) and fecal lactoferrin (FL) levels with the disease activity according to 3 different disease activity indices and to investigate the relationship between the presence of peri-nuclear anti-neutrophil antibody (p-ANCA) and disease activity. |
| format | Article |
| id | doaj-art-04f1a8b07317402e8245dc105319597a |
| institution | Kabale University |
| issn | 2284-5623 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Laboratory Medicine |
| spelling | doaj-art-04f1a8b07317402e8245dc105319597a2025-02-10T13:26:16ZengSciendoRomanian Journal of Laboratory Medicine2284-56232025-01-01331515810.2478/rrlm-2025-0001Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activityBüşra Usta0Demet Gür Vural1Asuman Birinci2Müge Ustaoğlu Dede3Medical Microbiology, Samsun Training and Research Hospital, TurkeyMedical Microbiology, Ondokuz Mayıs University, TurkeyMedical Microbiology, Ondokuz Mayıs University, TurkeyDepartment of Gastroenterology, Ondokuz Mayıs University, TurkeyAlthough colonoscopy remains the gold standard for Ulcerative colitis (UC) diagnosis due to its invasive and costly nature, non-invasive biomarkers are gaining importance in disease activity monitoring and diagnosis. In our study, we aimed to evaluate the correlation of fecal calprotectin (FC) and fecal lactoferrin (FL) levels with the disease activity according to 3 different disease activity indices and to investigate the relationship between the presence of peri-nuclear anti-neutrophil antibody (p-ANCA) and disease activity.https://doi.org/10.2478/rrlm-2025-0001ancacalprotectindisease activitylactoferrin |
| spellingShingle | Büşra Usta Demet Gür Vural Asuman Birinci Müge Ustaoğlu Dede Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity Romanian Journal of Laboratory Medicine anca calprotectin disease activity lactoferrin |
| title | Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity |
| title_full | Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity |
| title_fullStr | Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity |
| title_full_unstemmed | Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity |
| title_short | Correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity |
| title_sort | correlation between fecal biomarkers and the presence of antineutrophil cytoplasmic antibodies with ulcerative colitis disease activity |
| topic | anca calprotectin disease activity lactoferrin |
| url | https://doi.org/10.2478/rrlm-2025-0001 |
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