Clinical significance of Cyclin D1 by complete quantification detection in mantle cell lymphoma: positive indicator in prognosis

Clinical significance of Cyclin D1 by complete quantification detection in mantle cell lymphoma: positive indicator in prognosis

Abstract Objectives The positive expression of Cyclin D1 in immunohistochemical (IHC) staining serves as the cornerstone for diagnosing mantle cell lymphoma (MCL). However, existing literature does not conclusively establish whether the expression ratio and staining intensity significantly influence...

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Bibliographic Details
Main Authors: Yan Yang, Liling Song, Ying Yin, Yuan Gao, Yunjun Wang, Shishou Wu, Jun Wang, Yu Pan, Xiaolong Sui, Lei Jiang, Yunyun Zhang, Guohua Yu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Diagnostic Pathology
Subjects:
Cyclin D1
QDB
MCL
Protein quantitation
Prognosis
Online Access:https://doi.org/10.1186/s13000-024-01577-z
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