Case Series of Q Fever Infection: A 15-year Experience at Sultan Qaboos University Hospital, Oman

Objectives: Q fever is a worldwide zoonosis, yet its prevalence may be underestimated due to the challenges in diagnosis. We present a series of cases where patients were treated for Q fever infection based primarily on their clinical features and available laboratory tests, highlighting the difficu...

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Main Authors: Kowthar S. Hassan, Batool Al Lawati, Turkiya Al-Siyabi
Format: Article
Language:English
Published: Oman Medical Specialty Board 2024-11-01
Series:Oman Medical Journal
Subjects:
Online Access:https://omjournal.org/articleDetails.aspx?coType=1&aId=3893
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author Kowthar S. Hassan
Batool Al Lawati
Turkiya Al-Siyabi
author_facet Kowthar S. Hassan
Batool Al Lawati
Turkiya Al-Siyabi
author_sort Kowthar S. Hassan
collection DOAJ
description Objectives: Q fever is a worldwide zoonosis, yet its prevalence may be underestimated due to the challenges in diagnosis. We present a series of cases where patients were treated for Q fever infection based primarily on their clinical features and available laboratory tests, highlighting the difficulties in establishing the diagnosis. Methods: This 15-year case series was observed from January 2009 to November 2023 at Sultan Qaboos University Hospital, Oman. Relevant patient information was obtained from the electronic hospital records under the ethical approval MREC # 3139. Results: We treated 17 patients from a total of 1481 patients tested. The median age was 38 years, with a male-to-female ratio of 1.4:1. Fever was the most common symptom, and six patients experienced weight loss. Hepatobiliary, respiratory, neurological, and musculoskeletal symptoms occurred in 10, six, five, and four patients, respectively. Three patients developed rashes during their illness. Two patients had definite infective endocarditis, one had probable infective endocarditis, and two patients had pericardial effusion. Conclusions: Q fever should be considered in the differential diagnosis of a wide range of clinical presentations. However, it can be clinically challenging, and serological test interpretation can be difficult in areas of endemicity and with limited diagnostic tests. A combination of compatible clinical illnesses and appropriate diagnostic tests is necessary for accurate diagnosis.
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spelling doaj-art-04e5f985d3f14edfb91eecd1309bd8902025-08-20T03:13:22ZengOman Medical Specialty BoardOman Medical Journal1999-768X2070-52042024-11-01396e691e69110.5001/omj.2024.110Case Series of Q Fever Infection: A 15-year Experience at Sultan Qaboos University Hospital, OmanKowthar S. Hassan0Batool Al Lawati1Turkiya Al-Siyabi2Infectious Diseases Unit, Department of Medicine, Sultan Qaboos University Hospital, Muscat, OmanRheumatology Unit, Department of Medicine, Sultan Qaboos University Hospital, Muscat, OmanDepartment of Microbiology and Immunology, Sultan Qaboos University Hospital, Muscat, OmanObjectives: Q fever is a worldwide zoonosis, yet its prevalence may be underestimated due to the challenges in diagnosis. We present a series of cases where patients were treated for Q fever infection based primarily on their clinical features and available laboratory tests, highlighting the difficulties in establishing the diagnosis. Methods: This 15-year case series was observed from January 2009 to November 2023 at Sultan Qaboos University Hospital, Oman. Relevant patient information was obtained from the electronic hospital records under the ethical approval MREC # 3139. Results: We treated 17 patients from a total of 1481 patients tested. The median age was 38 years, with a male-to-female ratio of 1.4:1. Fever was the most common symptom, and six patients experienced weight loss. Hepatobiliary, respiratory, neurological, and musculoskeletal symptoms occurred in 10, six, five, and four patients, respectively. Three patients developed rashes during their illness. Two patients had definite infective endocarditis, one had probable infective endocarditis, and two patients had pericardial effusion. Conclusions: Q fever should be considered in the differential diagnosis of a wide range of clinical presentations. However, it can be clinically challenging, and serological test interpretation can be difficult in areas of endemicity and with limited diagnostic tests. A combination of compatible clinical illnesses and appropriate diagnostic tests is necessary for accurate diagnosis.https://omjournal.org/articleDetails.aspx?coType=1&aId=3893q fevercoxiellaomanserologic testsendocarditishepatitissystemic lupus erythematosusarthritisrheumatoid
spellingShingle Kowthar S. Hassan
Batool Al Lawati
Turkiya Al-Siyabi
Case Series of Q Fever Infection: A 15-year Experience at Sultan Qaboos University Hospital, Oman
Oman Medical Journal
q fever
coxiella
oman
serologic tests
endocarditis
hepatitis
systemic lupus erythematosus
arthritis
rheumatoid
title Case Series of Q Fever Infection: A 15-year Experience at Sultan Qaboos University Hospital, Oman
title_full Case Series of Q Fever Infection: A 15-year Experience at Sultan Qaboos University Hospital, Oman
title_fullStr Case Series of Q Fever Infection: A 15-year Experience at Sultan Qaboos University Hospital, Oman
title_full_unstemmed Case Series of Q Fever Infection: A 15-year Experience at Sultan Qaboos University Hospital, Oman
title_short Case Series of Q Fever Infection: A 15-year Experience at Sultan Qaboos University Hospital, Oman
title_sort case series of q fever infection a 15 year experience at sultan qaboos university hospital oman
topic q fever
coxiella
oman
serologic tests
endocarditis
hepatitis
systemic lupus erythematosus
arthritis
rheumatoid
url https://omjournal.org/articleDetails.aspx?coType=1&aId=3893
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AT batoolallawati caseseriesofqfeverinfectiona15yearexperienceatsultanqaboosuniversityhospitaloman
AT turkiyaalsiyabi caseseriesofqfeverinfectiona15yearexperienceatsultanqaboosuniversityhospitaloman