C leistopholis patens root bark extract exerts cardioprotective effect against doxorubicin-induced myocardial toxicity in rats

C leistopholis patens root bark extract exerts cardioprotective effect against doxorubicin-induced myocardial toxicity in rats

Abstract Background Myocardial Infarction still persists as the most prevalent cardiovascular disease and is a top cause of morbidity and mortality in doxorubicin treated cancer patients. This study evaluated the prophylactic effect of the ethanol root bark extract of Cleistopholis patens (ERBECP) a...

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Main Authors: Chidinma Pamela Ononiwu, Parker Elijah Joshua, Christian Chijioke Amah, Rita Onyekachukwu Asomadu, Ekezie Matthew Okorigwe, Chukwubuikem Stephen Nnemolisa, Timothy Prince Chidike Ezeorba, Valentine Odirachukwumma Nwanelo, Favour Chinagorom Iyidiegwu, Justin Onuawuchi Duru, Peace Nkiruka Okeke, Onyinyechi Becky Adiele
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Laboratory Animal Research
Subjects:
Myocardial infarction
Doxorubicin
Cleistopholis patens
Cardiotoxicity
Oxidative stress
Histopathology
Online Access:https://doi.org/10.1186/s42826-024-00225-3
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