Synthesis of lactic acid from glucose catalyzed by MOFs

Lactic acid is the monomer for the synthesis of polylactic acid (PLA), a biodegradable plastic. In industry, lactic acid is mainly produced through the fermentation of glucose, but the space-time yield of this process is relatively low. Therefore, the catalytic conversion of glucose to lactic acid h...

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Bibliographic Details
Main Authors: Longfei Yan, Lijuan Su, Yu Zhang, Qihui Zhang, Bin Wu, Fuweng Zhang, Weiping Deng
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Applied Catalysis O: Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950648425000264
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Summary:Lactic acid is the monomer for the synthesis of polylactic acid (PLA), a biodegradable plastic. In industry, lactic acid is mainly produced through the fermentation of glucose, but the space-time yield of this process is relatively low. Therefore, the catalytic conversion of glucose to lactic acid has garnered significant attention as an alternative approach. In this study, Metal-Organic Frameworks (MOFs) were employed to catalyze the conversion of glucose in methanol to synthesize methyl lactate. The bonding modes of Al3+ with different ligands in Al-MOF result in variations in the ratios of Lewis acid to Brønsted acid, influencing the catalytic performance of Al-MOF. Among them, MIL-120, formed through the complete coordination of Al3+ with the four carboxyl groups of pyromellitic acid, exhibits the most suitable ratio of Lewis acid to Brønsted acid. Using MIL-120 as a catalyst, glucose was completely converted, achieving a methyl lactate yield of 43 % in methanol at 463 K and 1 MPa N2 for 2 h.
ISSN:2950-6484