Altered resting-state functional connectivity of the frontal-striatal circuit in elderly with apathy.

Altered resting-state functional connectivity of the frontal-striatal circuit in elderly with apathy.

Apathy is defined as reduction of goal-directed behaviors and a common nuisance syndrome of neurodegenerative and psychiatric disease. The underlying mechanism of apathy implicates changes of the front-striatal circuit, but its precise alteration is unclear for apathy in healthy aged people. The aim...

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Bibliographic Details
Main Authors: Chizuko Hamada, Toshikazu Kawagoe, Masahiro Takamura, Atsushi Nagai, Shuhei Yamaguchi, Keiichi Onoda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261334&type=printable
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