Clinical Syndrome of Seizures, Headache, and Visual Blurring in Metastatic Carcinoma Colon
A 51-year-old lady diagnosed as a case of metastatic carcinoma colon stage IV involving lung and left adrenal metastasis was initiated with palliative chemotherapy with FOLFOX-6 chemotherapy infusion regimen that consisted of 5-flurouracil, calcium leucovorin, and oxaliplatin and injection bevacizum...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2024-02-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1772710 |
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| author | Lakshmi Raj T.M. Anoop Rakesh CA |
| author_facet | Lakshmi Raj T.M. Anoop Rakesh CA |
| author_sort | Lakshmi Raj |
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| description | A 51-year-old lady diagnosed as a case of metastatic carcinoma colon stage IV involving lung and left adrenal metastasis was initiated with palliative chemotherapy with FOLFOX-6 chemotherapy infusion regimen that consisted of 5-flurouracil, calcium leucovorin, and oxaliplatin and injection bevacizumab was added to cycle seven of FOLFOX-6 chemotherapy. After 2 months of initiating bevacizumab, she was presented with one episode of generalized tonic clonic seizure, headache, and visual blurring of 2 days duration and magnetic resonance imaging brain T2 fluid-attenuated inversion recovery image revealed subcortical white matter edema in bilateral frontoparietal, occipital, left temporal lobes (Fig. 1A and B), and hyperintense edema with effacement of folia in both cerebellum with nodular areas of contrast enhancement suggestive of posterior reversible encephalopathy syndrome. |
| format | Article |
| id | doaj-art-04a2e0064ed84d26bb80fdb8c7ce4a43 |
| institution | OA Journals |
| issn | 0971-5851 0975-2129 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-04a2e0064ed84d26bb80fdb8c7ce4a432025-08-20T02:22:34ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292024-02-01450106406510.1055/s-0043-1772710Clinical Syndrome of Seizures, Headache, and Visual Blurring in Metastatic Carcinoma ColonLakshmi Raj0T.M. Anoop1https://orcid.org/0000-0003-0567-5253Rakesh CA2Department of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, IndiaDepartment of Medical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, IndiaDepartment of Radiodiagnosis, Regional Cancer Centre, Thiruvananthapuram, Kerala, IndiaA 51-year-old lady diagnosed as a case of metastatic carcinoma colon stage IV involving lung and left adrenal metastasis was initiated with palliative chemotherapy with FOLFOX-6 chemotherapy infusion regimen that consisted of 5-flurouracil, calcium leucovorin, and oxaliplatin and injection bevacizumab was added to cycle seven of FOLFOX-6 chemotherapy. After 2 months of initiating bevacizumab, she was presented with one episode of generalized tonic clonic seizure, headache, and visual blurring of 2 days duration and magnetic resonance imaging brain T2 fluid-attenuated inversion recovery image revealed subcortical white matter edema in bilateral frontoparietal, occipital, left temporal lobes (Fig. 1A and B), and hyperintense edema with effacement of folia in both cerebellum with nodular areas of contrast enhancement suggestive of posterior reversible encephalopathy syndrome.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1772710bevacizumabmedical oncologyposterior reversible encephalopathy syndrome (PRES)magnetic resonance imaging |
| spellingShingle | Lakshmi Raj T.M. Anoop Rakesh CA Clinical Syndrome of Seizures, Headache, and Visual Blurring in Metastatic Carcinoma Colon Indian Journal of Medical and Paediatric Oncology bevacizumab medical oncology posterior reversible encephalopathy syndrome (PRES) magnetic resonance imaging |
| title | Clinical Syndrome of Seizures, Headache, and Visual Blurring in Metastatic Carcinoma Colon |
| title_full | Clinical Syndrome of Seizures, Headache, and Visual Blurring in Metastatic Carcinoma Colon |
| title_fullStr | Clinical Syndrome of Seizures, Headache, and Visual Blurring in Metastatic Carcinoma Colon |
| title_full_unstemmed | Clinical Syndrome of Seizures, Headache, and Visual Blurring in Metastatic Carcinoma Colon |
| title_short | Clinical Syndrome of Seizures, Headache, and Visual Blurring in Metastatic Carcinoma Colon |
| title_sort | clinical syndrome of seizures headache and visual blurring in metastatic carcinoma colon |
| topic | bevacizumab medical oncology posterior reversible encephalopathy syndrome (PRES) magnetic resonance imaging |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1772710 |
| work_keys_str_mv | AT lakshmiraj clinicalsyndromeofseizuresheadacheandvisualblurringinmetastaticcarcinomacolon AT tmanoop clinicalsyndromeofseizuresheadacheandvisualblurringinmetastaticcarcinomacolon AT rakeshca clinicalsyndromeofseizuresheadacheandvisualblurringinmetastaticcarcinomacolon |