Classification of schizophrenia, bipolar disorder and major depressive disorder with comorbid traits and deep learning algorithms

Abstract Many psychiatric disorders share genetic liabilities, but whether these shared liabilities can be utilized to classify and differentiate psychiatric disorders remains unclear. In this study, we use polygenic risk scores (PRSs) of 42 traits comorbid with schizophrenia (SCZ), bipolar disorder...

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Bibliographic Details
Main Authors: Xiangning Chen, Yimei Lu, Joan Manuel Cue, Mira V. Han, Vishwajit L. Nimgaonkar, Daniel R. Weinberger, Shizhong Han, Zhongming Zhao, Jingchun Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-025-00564-7
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